Anti-CD19 抗体 [MB19-1] (PE/Cy5.5 ®) (ab25384)

製品の概要

  • 製品名Anti-CD19 antibody [MB19-1] (PE/Cy5.5 ®)
    CD19 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MB19-1] to CD19 (PE/Cy5.5 ®)
  • 標識PE/Cy5.5 ®. Ex: 496nm, Em: 690nm
  • 特異性CD19 B cell differentiation antigen, Mr 95 kDa.
  • アプリケーション適用あり: Flow Cyt, IPmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    CD19+ mouse pre-B cell line, 300.19

  • ポジティブ・コントロール
    • Mature B cells. All splenic and peritoneal IgM+ cells of B1 and B2 lineages.
  • 特記事項To ensure consistency of performance, each batch of monoclonal antibody is tested by flow cytometry to conform to characteristics of a standard reference reagent. This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab25384 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
IP
  • 追加情報Flow Cyt: Use up to 0.2µg to label 106 cells.
    IP: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
    • 関連疾患Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) [MIM:613493]; also called antibody deficiency due to CD19 defect. CVID3 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
    • 配列類似性Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    • 翻訳後修飾Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Antibody deficiency due to defect in CD19, included antibody
      • AW495831 antibody
      • B lymphocyte antigen CD19 antibody
      • B lymphocyte surface antigen B4 antibody
      • B-lymphocyte antigen CD19 antibody
      • B-lymphocyte surface antigen B4 antibody
      • B4 antibody
      • CD19 antibody
      • CD19 antigen antibody
      • CD19 molecule antibody
      • Cd19 protein antibody
      • CD19_HUMAN antibody
      • CVID3 antibody
      • Differentiation antigen CD19 antibody
      • Leu 12 antibody
      • Leu-12 antibody
      • Leu12 antibody
      • MGC109570 antibody
      • MGC12802 antibody
      • T-cell surface antigen Leu-12 antibody
      see all

    Anti-CD19 antibody [MB19-1] (PE/Cy5.5 ®) (ab25384) 使用論文

    ab25384 has not yet been referenced specifically in any publications.

    Product Wall

    Application Flow Cytometry
    Sample Dog Cell (Whole blood)
    Permeabilization No
    Gating Strategy Lymphocytes
    Specification Whole blood
    Preparation Cell harvesting/tissue preparation method: Whole blood washed in PBS and lysed
    Sample buffer: PBS
    Username

    Anushka George

    Verified customer

    投稿 Mar 15 2016

    Thank you for contacting us.

    Please check the following antibodies;


    http://www.abcam.com/cd19-antibody-6d5-pe-cy5-5-ab25548.html

    http://www.abcam.com/cd19-antibody-mb19-1-pe-cy5-5-ab25384.html

    I hope this inform...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"