Anti-CD16+CD32 抗体 [93] (PE/Cy5.5 ®) (ab25039)

製品の概要

  • 製品名Anti-CD16+CD32 antibody [93] (PE/Cy5.5 ®)
    CD16+CD32 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [93] to CD16+CD32 (PE/Cy5.5 ®)
  • 標識PE/Cy5.5 ®. Ex: 496nm, Em: 690nm
  • アプリケーション適用あり: Flow Cyt, Blockingmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • エピトープThis antibody recognizes a conformational epitope formed by Fc gamma II and Fc gamma III receptors.
  • 特記事項This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.


    This antibody besides identifying Fcgamma R+ cells, has been used to block Fc receptor binding of IgG, Fc mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on Fc gamma R for parasitic invasion.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 16% Sucrose, PBS; Stabilizing agent
  • Concentration information loading...
  • 精製度IgG fraction
  • 一次抗体 備考This antibody besides identifying Fcgamma R+ cells, has been used to block Fc receptor binding of IgG, Fc mediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on Fc gamma R for parasitic invasion.
  • ポリ/モノモノクローナル
  • クローン名93
  • アイソタイプIgG2b
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab25039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.2µg for 106 cells. ab154456-Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
Blocking Use at an assay dependent concentration.

ターゲット情報

  • 関連性Function: Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. Tissue specificity: Found on monocytes, neutrophils and eosinophil platelets. Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. PTM: Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
  • 細胞内局在CD32: Type I membrane protein. CD16: Attached to the membrane by a GPI anchor. Exists also as a soluble receptor, produced by a proteolytic cleavage.
  • 参照データベース
  • 別名
    • CD16a antibody
    • CD16b antibody
    • CD32 antibody
    • CD32A antibody
    • CD32B antibody
    • CDw32 antibody
    • Fc fragment of IgG low affinity IIa receptor antibody
    • Fc fragment of IgG low affinity IIb receptor antibody
    • Fc fragment of IgG low affinity IIIa receptor antibody
    • Fc fragment of IgG low affinity IIIb receptor antibody
    • Fc gamma receptor III A antibody
    • Fc gamma receptor IIIb antibody
    • Fc gamma RIIa antibody
    • Fc gamma RIIb antibody
    • Fc gamma RIII beta antibody
    • Fc-gamma RII-a antibody
    • Fc-gamma-RIIa antibody
    • FCG2A_HUMAN antibody
    • FcGR antibody
    • FCGR2A antibody
    • FCGR2B antibody
    • FCGR3 antibody
    • FCGR3A antibody
    • FCGR3B antibody
    • FcRII-a antibody
    • FcRIII antibody
    • IgG Fc receptor II-a antibody
    • Low affinity immunoglobulin gamma Fc region receptor II-a antibody
    see all

Anti-CD16+CD32 antibody [93] (PE/Cy5.5 ®) 画像

  • Flow cytometry analysis of BALB/c mouse splenocytes labeling CD16 + CD32 with ab25039 at 0.1 µg/106cells and CD19 with Rat Anti-Mouse CD19-PE.

Anti-CD16+CD32 antibody [93] (PE/Cy5.5 ®) (ab25039) 使用論文

ab25039 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"