Anti-CD147 抗体 [MEM-M6/1] (Biotin) (ab21898)

製品の概要

• 製品名Anti-CD147 antibody [MEM-M6/1] (Biotin)
  CD147 一次抗体 製品一覧
• 製品の詳細
  Mouse monoclonal [MEM-M6/1] to CD147 (Biotin)
• 標識Biotin
• アプリケーション適用あり: Flow Cyt, IP, WBmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Recombinant full length protein (Human): Protein A CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2 and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimmer).

• エピトープThe epitope is localised in the N terminal Ig domain (D1) of CD147 antigen.
• 特記事項

  
  

  ab21898 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.

  The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

製品の特性

• 製品の状態Liquid
• 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• バッファーPreservative: 15mM Sodium Azide
  Constituents: PBS, pH 7.4
• Concentration information loading...
• 精製度Protein G purified
• 一次抗体 備考ab21898 is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
• ポリ/モノモノクローナル
• クローン名MEM-M6/1
• アイソタイプIgG1
• 研究分野
  • Immunology
  • Cell Type Markers
  • CD
  • Endothelial Cells

  • Neuroscience
  • Sensory System
  • Visual system

  • Neuroscience
  • Neurology process
  • Neurogenesis

  • Cancer
  • Invasion/microenvironment
  • ECM
  • Extracellular matrix
  • Other

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Types of disease
  • Cancer

  • Cardiovascular
  • Angiogenesis
  • Endothelial Cell Markers

関連製品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

アプリケーション

ターゲット情報

• 機能Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
• 組織特異性Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
• 配列類似性Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  Contains 1 Ig-like V-type (immunoglobulin-like) domain.
• 翻訳後修飾N-glycosylated.
• 細胞内局在Cell membrane. Melanosome. Colocalizes with SLC16A1 and SLC16A8 (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

• Target information above from: UniProt accession P35613 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 682 Human
  • Omim: 109480 Human
  • SwissProt: P35613 Human
  • Unigene: 501293 Human
• 別名
  • 5A11 antigen antibody
  • 5F7 antibody
  • BASI_HUMAN antibody

  • Basigin (Ok blood group) antibody
  • Basigin antibody
  • Blood brain barrier HT7 antigen antibody
  • Bsg antibody
  • CD 147 antibody
  • CD147 antibody
  • CD147 antigen antibody
  • Collagenase stimulatory factor antibody
  • EMMPRIN antibody
  • Extracellular matrix metalloproteinase inducer antibody
  • Leukocyte activation antigen M6 antibody
  • M 6 antibody
  • M6 antibody
  • M6 leukocyte activation antigen antibody
  • Neurothelin antibody
  • OK antibody
  • OK blood group antibody
  • OK blood group antigen antibody
  • TCSF antibody
  • Tumor cell derived collagenase stimulatory factor antibody
  • Tumor cell-derived collagenase stimulatory factor antibody

  see all