製品の概要

  • 製品名
    Anti-CD14 antibody [RPA-M1]
    CD14 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [RPA-M1] to CD14
  • アプリケーション
    適用あり: Flow Cytmore details
  • 種交差性
    交差種: Human
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • ポジティブ・コントロール
    • Human monocytes

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab86895 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報
    Flow Cyt: Use 0.1 - 0.2 µg for 106 cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
    • 組織特異性
      Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
    • 配列類似性
      Contains 11 LRR (leucine-rich) repeats.
    • 翻訳後修飾
      N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
    • 細胞内局在
      Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CD 14 antibody
      • CD_antigen=CD14 antibody
      • CD14 antibody
      • CD14 antigen antibody
      • CD14 molecule antibody
      • CD14_HUMAN antibody
      • LPS-R antibody
      • Mo2 antibody
      • Monocyte differentiation antigen CD14 antibody
      • Monocyte differentiation antigen CD14 urinary form antibody
      • Monocyte differentiation antigen CD14, membrane-bound form antibody
      • Myeloid cell specific leucine rich glycoprotein antibody
      • Myeloid cell-specific leucine-rich glycoprotein antibody
      see all

    画像

    • Cell surface flow cytometric analysis of CD14 in human monocytes, using 0.1 µg of ab86895 for 106 cells. Anti mouse IgG-FITC was the secondary antibody used for this test.
      Shaded histogram represents cells without antibody; green represents isotype control; red represents anti CD14 antibody.

    プロトコール

    参考文献

    This product has been referenced in:
    • Brito BE  et al. Toll-like receptor 4 and CD14 expression in human ciliary body and TLR-4 in human iris endothelial cells. Exp Eye Res 79:203-8 (2004). Read more (PubMed: 15325567) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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