製品の概要

  • 製品名
    Anti-CD14 antibody [MEM-15]
    CD14 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MEM-15] to CD14
  • 由来種
    Mouse
  • 特異性
    This antibody reacts with CD14 antigen
  • アプリケーション
    適用あり: Flow Cyt, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Non human primates
  • 免疫原

    A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab760 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use a concentration of 4 µg/ml.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

IP Use at an assay dependent concentration.

ターゲット情報

  • 機能
    Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
  • 組織特異性
    Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
  • 配列類似性
    Contains 11 LRR (leucine-rich) repeats.
  • 翻訳後修飾
    N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CD 14 antibody
    • CD_antigen=CD14 antibody
    • CD14 antibody
    • CD14 antigen antibody
    • CD14 molecule antibody
    • CD14_HUMAN antibody
    • LPS-R antibody
    • Mo2 antibody
    • Monocyte differentiation antigen CD14 antibody
    • Monocyte differentiation antigen CD14 urinary form antibody
    • Monocyte differentiation antigen CD14, membrane-bound form antibody
    • Myeloid cell specific leucine rich glycoprotein antibody
    • Myeloid cell-specific leucine-rich glycoprotein antibody
    see all

参考文献

This product has been referenced in:
  • Lin HT  et al. Characterization of pancreatic stem cells derived from adult human pancreas ducts by fluorescence activated cell sorting. World J Gastroenterol 12:4529-35 (2006). Read more (PubMed: 16874866) »
  • Sundan A  et al. Soluble CD14 from urine copurifies with a potent inducer of cytokines. Eur J Immunol 24:1779-84 (1994). Read more (PubMed: 7519994) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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