製品の概要

  • 製品名Anti-CD11a antibody [I21/7] (PE/Cy7 ®)
    CD11a 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [I21/7] to CD11a (PE/Cy7 ®)
  • 標識PE/Cy7 ®. Ex: 496nm, Em: 774nm
  • 特異性This antibody reacts with the alpha subunit of mouse CD11a.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    The details of the immunogen for this antibody are not available.

  • 特記事項This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab51220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 0.2µg for 106 cells.

ab154460 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
  • 組織特異性Leukocytes.
  • 配列類似性Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
    Contains 1 VWFA domain.
  • ドメインThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Lymphocyte function associated antigen, type 1, alpha subunit antibody
    • Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody
    • Antigen CD11A antibody
    • CD 11a antibody
    • CD11 antigen-like family member A antibody
    • CD11a antibody
    • CD11a antigen antibody
    • Integrin Alpha L antibody
    • Integrin alpha-L antibody
    • Integrin gene promoter antibody
    • Integrin, alpha L (antigen CD11A (p180), lymphocyte function associated antigen 1; alpha polypeptide) antibody
    • ITAL_HUMAN antibody
    • Itgal antibody
    • ITGAL protein antibody
    • Leukocyte adhesion glycoprotein LFA 1 alpha chain antibody
    • Leukocyte adhesion glycoprotein LFA-1 alpha chain antibody
    • Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain antibody
    • Leukocyte function associated molecule 1 alpha chain antibody
    • Leukocyte function-associated molecule 1 alpha chain antibody
    • LFA 1 alpha (LFA1A) antibody
    • LFA 1 alpha antibody
    • LFA 1 antibody
    • LFA 1A antibody
    • LFA-1A antibody
    • LFA1A antibody
    • Ly15 antibody
    • Ly21 antibody
    • Lymphocyte function associated antigen 1 antibody
    • Lymphocyte Function Associated Antigen Type 1 alpha antibody
    • lymphocyte function-associated antigen 1, alpha polypeptide antibody
    • p180 antibody
    see all

Anti-CD11a antibody [I21/7] (PE/Cy7 ®) 画像

  • Flow cytometry analysis staining CD11a in mouse splenocytes using ab51220 at a dilution of 0.3 ug/106 cells.

Anti-CD11a antibody [I21/7] (PE/Cy7 ®) (ab51220) 使用論文

This product has been referenced in:
  • Kamata M  et al. ICAM-1 Deficiency Exacerbates Sarcoid-Like Granulomatosis Induced by Propionibacterium acnes through Impaired IL-10 Production by Regulatory T Cells. Am J Pathol 183:1731-9 (2013). Read more (PubMed: 24103557) »
  • de Groot D  et al. Targeted deletion of the inhibitory NF-kappaB p50 subunit in bone marrow-derived cells improves collateral growth after arterial occlusion. Cardiovasc Res 88:179-85 (2010). Read more (PubMed: 20495189) »

See all 2 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Flow Cytometry
Sample Mouse Cell (whole blood)
Specification whole blood
Permeabilization No
Gating Strategy monocytes and granulocytes
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投稿 May 01 2012

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"