Anti-CD105 抗体 [MEM-229] (Phycoerythrin) (ab53321)

製品の概要

  • 製品名Anti-CD105 antibody [MEM-229] (Phycoerythrin)
    CD105 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [MEM-229] to CD105 (Phycoerythrin)
  • 標識Phycoerythrin. Ex: 488nm, Em: 575nm
  • アプリケーション適用あり: WB, IHC-Fr, ICC, Flow Cytmore details
  • 種交差性
    交差種: Human, Pig
  • 免疫原

    Recombinant vaccinia virus containing human CD105 (L-isoform) cDNA

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab53321 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Use under non reducing condition. Predicted molecular weight: 71 kDa.
IHC-Fr 1/200. Fix with acetone.
ICC Use at an assay dependent concentration.
Flow Cyt Use 20µl for 106 cells. (or 100µl of whole blood).



ab91363-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 機能Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
  • 組織特異性Endoglin is restricted to endothelial cells in all tissues except bone marrow.
  • 関連疾患Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AI528660 antibody
    • AI662476 antibody
    • CD 105 antibody
    • CD105 antibody
    • CD105 antigen antibody
    • EGLN_HUMAN antibody
    • END antibody
    • Endoglin antibody
    • Eng antibody
    • FLJ41744 antibody
    • HHT1 antibody
    • ORW antibody
    • ORW1 antibody
    • Osler Rendu Weber syndrome 1 antibody
    • RP11 228B15.2 antibody
    • S-endoglin antibody
    • SN6 antibody
    see all

Anti-CD105 antibody [MEM-229] (Phycoerythrin) 画像

  • ab53318 staining CD105 in infarcted porcine heart by Immunohistochemistry (Frozen sections). Cell nuclei were counterstained blue with DAPI.

Anti-CD105 antibody [MEM-229] (Phycoerythrin) (ab53321) 使用論文

This product has been referenced in:
  • Haidari M  et al. Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-ß-dependent vascular endothelial cadherin tyrosine phosphorylation. Cardiovasc Diabetol 13:112 (2014). Human . Read more (PubMed: 25027642) »
  • Kronsteiner B  et al. Human Mesenchymal Stem Cells from Adipose Tissue and Amnion Influence T-Cells Depending on Stimulation Method and Presence of Other Immune Cells. Stem Cells Dev : (2011). Flow Cyt ; Human . Read more (PubMed: 21381973) »

See all 2 Publications for this product

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Attached please find the list of our antibodies that have been validated for use in Flow Cytometry on sheep cells.

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The IgG concentration of lot GR37350 is 60ug/ml.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Thank you for your enquiry. I am afraid that according to the supplier of the product, the exact concentration for this product is proprietary and can not be released. The only information they will provide is the number of tests and dilution facto...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"