製品の概要

  • 製品名Anti-CCKAR antibody
    CCKAR 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CCKAR
  • アプリケーション適用あり: ICC, IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Dog
  • 免疫原

    Synthetic peptide:

    TGASLSRFSYSHMSASVPPQ

    conjugated to KLH, corresponding to amino acids 409-428 of Human CCKAR

  • ポジティブ・コントロール
    • HEK293 cells that have been transfected to express CCK1.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab28627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC 1/1000.
IHC-P 1/500.
WB 1/1000. Detects a band of approximately 80-90 kDa.

ターゲット情報

  • 関連性The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A (CCKAR)and B (CCKBR), based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, and potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth and tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, and regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, and drug addiction.
  • 細胞内局在Integral membrane protein
  • 参照データベース
  • 別名
    • CCK A antibody
    • CCK A receptor antibody
    • CCK AR antibody
    • CCK-A receptor antibody
    • CCK1 R antibody
    • CCK1-R antibody
    • CCK1R antibody
    • CCKA antibody
    • CCKA receptor antibody
    • CCKR Type A antibody
    • CCKRA antibody
    • Cholecystokinin 1 receptor antibody
    • Cholecystokinin A receptor antibody
    • Cholecystokinin receptor type A antibody
    • Cholecystokinin type A receptor antibody
    see all

Anti-CCKAR antibody 画像

  • ab28627 staining Human CCKAR in Human gastric mucosa by immunohistochemistry using paraffin embedded tissue.

Anti-CCKAR antibody (ab28627) 使用論文

This product has been referenced in:
  • Gonzalez-Coto AF  et al. Expression of cholecystokinin, gastrin, and their receptors in the mouse cornea. Invest Ophthalmol Vis Sci 55:1965-75 (2014). Mouse . Read more (PubMed: 24576871) »

See 1 Publication for this product

Product Wall

Thank you for your enquiry. I am sorry we do not supply this peptide as one of our products. The sequence of the immunogen used is TGASLSRFSYSHMSASVPPQ. I hope this has helped. Please do get back to me if you have any more queries. With thanks.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"