製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CCKAR
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Guinea pig
  • 免疫原

    Poly Lysin conjugated synthetic peptide:

    RFLLPPNDVMQQSWH

    , corresponding to amino acids 197-210 of Human CCKAR.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab14441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000. Detects a band of approximately 48 kDa.

ターゲット情報

  • 関連性
    The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A (CCKAR)and B (CCKBR), based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, and potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth and tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, and regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, and drug addiction.
  • 細胞内局在
    Integral membrane protein
  • 参照データベース
  • 別名
    • CCK A antibody
    • CCK A receptor antibody
    • CCK AR antibody
    • CCK-A receptor antibody
    • CCK1 R antibody
    • CCK1-R antibody
    • CCK1R antibody
    • CCKA antibody
    • CCKA receptor antibody
    • CCKR Type A antibody
    • CCKRA antibody
    • Cholecystokinin 1 receptor antibody
    • Cholecystokinin A receptor antibody
    • Cholecystokinin receptor type A antibody
    • Cholecystokinin type A receptor antibody
    see all

プロトコール

Anti-CCKAR antibody (ab14441) 使用論文

ab14441 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunocytochemistry
Sample
Human Cultured Cells (transfected HEK293)
Specification
transfected HEK293
Fixative
Methanol
Permeabilization
Yes - 0.3%TritonX-100
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 25°C
Username

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投稿 Sep 14 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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