製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CCKAR
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide, corresponding to the 3rd cytoplasmic domain of Human CCKAR.

  • ポジティブ・コントロール
    • Human adrenal and prostate tissues.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 10 µg/ml. requires pre-treatment with Proteinase K.

ターゲット情報

  • 関連性
    The cholecystokinin (CCK) family of peptide hormones have been implicated in numerous important physiologic events. These appear to be mediated through 2 general classes of receptors, A (CCKAR)and B (CCKBR), based on their binding affinities for CCK/gastrin family peptides. Through binding to class A receptors, CCK is a major physiologic mediator of gallbladder contraction and pancreatic enzyme secretion. It appears to play a role in slowing gastric emptying, relaxation of the sphincter of Oddi, and potentiation of insulin secretion. Further, it has been implicated as a mediator of pancreatic growth and tumorigenesis. Class A receptors have also been described in the anterior pituitary, myenteric plexus, and regions of the central nervous system, where they have been implicated in the pathogenesis of feeding disorders, Parkinson disease, schizophrenia, and drug addiction.
  • 細胞内局在
    Integral membrane protein
  • 参照データベース
  • 別名
    • CCK A antibody
    • CCK A receptor antibody
    • CCK AR antibody
    • CCK-A receptor antibody
    • CCK1 R antibody
    • CCK1-R antibody
    • CCK1R antibody
    • CCKA antibody
    • CCKA receptor antibody
    • CCKR Type A antibody
    • CCKRA antibody
    • Cholecystokinin 1 receptor antibody
    • Cholecystokinin A receptor antibody
    • Cholecystokinin receptor type A antibody
    • Cholecystokinin type A receptor antibody
    see all

画像

  • ab115287, at 10µg/ml, staining CCKAR in Formalin-fixed, Paraffin-embedded Human Prostate tissue by Immunohistochemistry.
  • ab115287, at 10µg/ml, staining CCKAR in Formalin-fixed, Paraffin-embedded Human Adrenal tissue by Immunohistochemistry.

プロトコール

参考文献

ab115287 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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