Anti-CCDC88C 抗体 (ab121235)
Key features and details
- Rabbit polyclonal to CCDC88C
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-CCDC88C antibody -
製品の詳細
Rabbit polyclonal to CCDC88C -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IF, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment corresponding to amino acids 1571-1698 of Human CCDC88C.
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ポジティブ・コントロール
- Human testis tissue
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab121235の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
Use a concentration of 1 - 4 µg/ml.
Recommend PFA Fixation and Triton X-100 treatment |
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IHC-P |
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6.0
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特記事項 |
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ICC/IF
Use a concentration of 1 - 4 µg/ml. Recommend PFA Fixation and Triton X-100 treatment |
IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. pH 6.0 |
ターゲット情報
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機能
Negative regulator of the canonical Wnt signaling pathway, acting downstream of DVL to inhibit CTNNB1/Beta-catenin stabilization. -
配列類似性
Belongs to the CCDC88 family. - Information by UniProt
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参照データベース
- Entrez Gene: 440193 Human
- Omim: 611204 Human
- SwissProt: Q9P219 Human
- Unigene: 525536 Human
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別名
- ccdc88c antibody
- Coiled-coil domain-containing protein 88C antibody
- DAPLE antibody
see all
画像
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Immunofluorescent staining of Human cell line A-431 shows positivity in nucleus and nucleoli. Recommended concentration of ab121235 1-4 µg/ml. Cells treated with PFA/Triton X-100.
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Immunohistochemical staining of paraffin embedded Human testis tissue, using 1/350 ab121235, shows strong nuclear positivity in cells of seminiferus ducts and Leydig cells.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab121235 は論文での使用が確認できていません。