製品の概要

  • 製品名Anti-CCDC6 antibody
    CCDC6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CCDC6
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Dog, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Orangutan, Xenopus tropicalis , Medaka fish
  • 免疫原

    Synthetic peptide corresponding to a region between residues 75 and 125 of Human CCDC6 (AAC60637.1).

  • ポジティブ・コントロール
    • HeLa whole cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab85923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2000 - 1/10000. Predicted molecular weight: 66 kDa.
IP Use at 2-5 µg/mg of lysate.

ターゲット情報

  • 組織特異性Ubiquitously expressed.
  • 関連疾患Defects in CCDC6 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving CCDC6 is found in thyroid papillary carcinomas. Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene.
  • ドメインThe protein has mostly an alpha helical conformation similar to myosin heavy-chain tail that might adopt a coiled-coil conformation.
  • 細胞内局在Cytoplasm. Cytoplasm > cytoskeleton. May be a cytoskeletal protein.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CCDC 6 antibody
    • CCDC6 antibody
    • CCDC6_HUMAN antibody
    • Coiled coil domain containing 6 antibody
    • Coiled coil domain containing protein 6 antibody
    • Coiled-coil domain-containing protein 6 antibody
    • D10S170 antibody
    • FLJ32286 antibody
    • H4 antibody
    • Papillary thyroid carcinoma encoded protein antibody
    • Papillary thyroid carcinoma-encoded protein antibody
    • Protein H4 antibody
    • PTC antibody
    • TPC antibody
    • TST 1 antibody
    • TST1 antibody
    see all

Anti-CCDC6 antibody 画像

  • All lanes : Anti-CCDC6 antibody (ab85923) at 0.1 µg/ml

    Lane 1 : HeLa whole cell lysate at 50 µg
    Lane 2 : HeLa whole cell lysate at 15 µg
    Lane 3 : HeLa whole cell lysate at 5 µg

    Developed using the ECL technique

    Predicted band size : 66 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)


    Exposure time : 30 seconds
  • Detection of Human CCDC6 in Immunoprecipitates of Whole cell lysate from HeLa cells (1 mg for IP, 20% of IP loaded) using ab85923 at 3 µg/mg lysate for IP and at 1 µg/ml for subsequent Western blot detection. Detection: Chemiluminescence with an exposure time of 10 seconds.

Anti-CCDC6 antibody (ab85923) 使用論文

ab85923 has not yet been referenced specifically in any publications.

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