製品の概要

  • 製品名Anti-CCDC50 antibody
    CCDC50 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CCDC50
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between residue 225 and 275 of Human CCDC50 (NP_777568.1).

  • ポジティブ・コントロール
    • Human breast carcinoma, osteosarcoma, ovarian carcinoma and stomach adenocarcinoma

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab101287 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.

ターゲット情報

  • 機能Involved in EGFR signaling.
  • 組織特異性Isoform 1 and isoform 2 are co-expressed in placenta, liver, lung, kidney and pancreas. Only isoform 1 is detected in skeletal muscle, brain and heart.
  • 関連疾患Defects in CCDC50 are the cause of deafness autosomal dominant type 44 (DFNA44) [MIM:607453]. A form of non-syndromic hearing loss. It is initially moderate and affects mainly low to mid frequencies. Later, it progresses to involve all the frequencies and leads to a profound hearing loss by the 6th decade. The onset of the hearing loss occurs in the first decade of life.
  • 翻訳後修飾Phosphorylated on tyrosine residues.
  • 細胞内局在Cytoplasm. Associated with microtubules of the cytoskeleton and mitotic apparatus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C3orf6 antibody
    • C3orf6 YMER antibody
    • CCD50_HUMAN antibody
    • CCDC 50 antibody
    • Ccdc50 antibody
    • Chromosome 3 open reading frame 6 antibody
    • Coiled coil domain containing 50 antibody
    • Coiled coil domain containing protein 50 antibody
    • Coiled-coil domain-containing protein 50 antibody
    • Protein Ymer antibody
    • Ymer antibody
    • Ymer protein antibody
    see all

Anti-CCDC50 antibody 画像

  • ab101287, at 1/250 dilution, staining CCDC50 in formalin-fixed paraffin-embedded Human ovarian carcinoma by Immunohistochemistry using DAB staining.

Anti-CCDC50 antibody (ab101287) 使用論文

ab101287 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"