製品の概要

  • 製品名Anti-CCBL1 antibody
    CCBL1 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to CCBL1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human CCBL1 (AAH33685)

  • ポジティブ・コントロール
    • Human liver tissue lysate, CCBL1 transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89067 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa.

ターゲット情報

  • 関連性CCBL1 is a cytosolic enzyme which is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism leads to the formation of reactive metabolites which can lead to nephrotoxicity and neurotoxicity. CCBL1 catalyzes the irreversible transamination of the L-tryptophan metabolite L-kinurenine to form kynurenic acid (KA). It catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. This enzyme has a central role in the bioactivation of nephrotoxic halogenated hydrocarbons - the possibility of human exposure to these chemicals has focused interest on the CCBL1 from human kidney.
  • 細胞内局在Cytoplasmic
  • 参照データベース
  • 別名
    • Beta lyase antibody
    • Beta lysase, kidney antibody
    • CCBL 1 antibody
    • Cysteine conjugate beta lyase antibody
    • Cysteine conjugate beta lyase, cytoplasmic antibody
    • Cysteine conjugate beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) antibody
    • Cysteine S conjugate beta lyase antibody
    • Cytoplasmic cysteine conjugate beta lyase antibody
    • FLJ95217 antibody
    • Glutamine phenylpyruvate aminotransferase antibody
    • Glutamine transaminase K antibody
    • GTK antibody
    • KAT1 antibody
    • KATI antibody
    • Kyneurenine aminotransferase antibody
    • Kynurenine aminotransferase I antibody
    • Kynurenine oxoglutarate transaminase 1 antibody
    • MGC29624 antibody
    • OTTHUMP00000022311 antibody
    • OTTHUMP00000022312 antibody
    see all

Anti-CCBL1 antibody 画像

  • Anti-CCBL1 antibody (ab89067) at 1 µg/ml + human liver tissue lysate at 50 µg

    Predicted band size : 41 kDa
  • All lanes : Anti-CCBL1 antibody (ab89067) at 1 µg/ml

    Lane 1 : CCBL1 transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 41 kDa
    Observed band size : 41 kDa
    Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.

Anti-CCBL1 antibody (ab89067) 使用論文

ab89067 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"