製品の概要

  • 製品名Anti-CC2D1A antibody
    CC2D1A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CC2D1A
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 1 and 50 of human CC2D1A (NP_060191.3).

  • ポジティブ・コントロール
    • Anaplastic thyroid carcinoma, breast carcinoma, colon carcinoma, ovarian carcinoma, prostate carcinoma, stomach adenocarcinoma.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab87279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500. Antigen retrieval with tris-EDTA buffer pH 9 recommended.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性CC2D1A belongs to the CC2D1 family. It contains one C2 domain. It is a transcription factor that binds specifically to the FRE (five repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. CC2D1A may play a role in the altered regulation of HTR1A associated with anxiety and major depression. It also mediates HDAC-independent repression of HTR1A promoter in neuronal cell. There are three named isoforms. Defects in CC2D1A are the cause of non-syndromic mental retardation autosomal recessive type 3 (MRT3). Patients display severe mental retardation and psychomotor development delay in early childhood. Non-syndromic mental retardation patients do not manifest other clinical signs.
    • 細胞内局在Cytoplasm. Nucleus.
    • 参照データベース
    • 別名
      • Akt kinase interacting protein 1 antibody
      • Coiled coil and C2 domain containing 1A antibody
      • Coiled coil and C2 domain containing protein 1A antibody
      • Five repressor element under dual repression binding protein 1 antibody
      • FLJ20241 antibody
      • FLJ41160 antibody
      • FRE under dual repression binding protein 1 antibody
      • FREUD 1 antibody
      • Freud 1/Aki1 antibody
      • Mental retardation, nonsyndromic, autosomal recessive, 3 antibody
      • MRT3 antibody
      • Putative NF kappa B activating protein 023N antibody
      • Putative NF kappa B activating protein antibody
      see all

    Anti-CC2D1A antibody 画像

    • ab87279, at a 1/250 dilution, staining CC2D1A in formalin fixed, paraffin embedded Human breast carcinoma tissue by Immunohistochemistry.
      Detection: DAB staining.
    • ab87279, at a 1/250 dilution, staining CC2D1A in formalin fixed, paraffin embedded Human thyroid carcinoma tissue by Immunohistochemistry.
      Detection: by DAB staining.
    • ab87279, at a 1/100 dilution, staining CC2D1A in formalin fixed, paraffin embedded Human prostate carcinoma tissue by Immunohistochemistry.

      Detection: Goat anti-Rabbit IgG conjugated with a red-fluorescent dye, at a 1/100 dilution.

    Anti-CC2D1A antibody (ab87279) 使用論文

    ab87279 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab87279.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"