製品の概要

  • 製品名Anti-cbx2 antibody
    CBX2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to cbx2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: EVQNRKRGKR PRGRPRKLTA MSSCSRRSKL KVGGCAGYAD PTSQHPLGVG GRQREGLGPS GRGWHFCQQS VPLLGKQEPP FFLSLSFCCQ GPQPAESSSP , corresponding to amino acids 66-166 of Human cbx2

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57890 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression.
    • 関連疾患Defects in CBX2 are the cause of 46,XY sex reversal type 5 (SRXY5) [MIM:613080]. It is a disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females.
    • 配列類似性Contains 1 A.T hook DNA-binding domain.
      Contains 1 chromo domain.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Cbx 2 antibody
      • CBX2 antibody
      • CBX2_HUMAN antibody
      • CDC A6 antibody
      • CDCA6 antibody
      • Cell division cycle associated 6 antibody
      • Cell division cycle associated6 antibody
      • chromobox homolog 2 (Pc class homolog, Drosophila) antibody
      • Chromobox homolog 2 antibody
      • Chromobox homolog2 antibody
      • Chromobox protein homolog 2 antibody
      • hromobox homolog 2 antibody
      • M33 antibody
      • M33 polycomb like antibody
      • MOD 2 antibody
      • MOD2 antibody
      • Modifier 3 antibody
      • Modifier3 antibody
      • Pc class homolog antibody
      • Polycomb antibody
      • SRXY5 antibody
      see all

    Anti-cbx2 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57890 cbx2 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-cbx2 antibody (ab57890) 使用論文

    ab57890 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57890.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"