Anti-Cathepsin K 抗体 - Catalytic domain (ab49893)

製品の概要

  • 製品名Anti-Cathepsin K antibody - Catalytic domain
    Cathepsin K 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Cathepsin K - Catalytic domain
  • 特異性ab49893 recognizes all three forms of Cathepsin K (but does not see the 258 amino acid form as well as the other two forms, due to a partial deletion of the sequence).
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide based on the catalytic domain of human Cathepsin K.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab49893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 37 kDa. A recommended starting concentration for Western blots is 1/1000 when using colorimetric substrates such as BCIP/NBT and 1/5000 for chemiluminescent substrates.

ターゲット情報

  • 機能Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation.
  • 組織特異性Predominantly expressed in osteclasts (bones).
  • 関連疾患Defects in CTSK are the cause of pycnodysostosis (PKND) [MIM:265800]. PKND is an autosomal recessive osteochondrodysplasia characterized by osteosclerosis and short stature.
  • 配列類似性Belongs to the peptidase C1 family.
  • 細胞内局在Lysosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cathepsin K antibody
    • Cathepsin O antibody
    • Cathepsin O1 antibody
    • Cathepsin O2 antibody
    • Cathepsin X antibody
    • CATK_HUMAN antibody
    • CTS02 antibody
    • Ctsk antibody
    • CTSO antibody
    • CTSO1 antibody
    • CTSO2 antibody
    • MGC23107 antibody
    • PKND antibody
    • PYCD antibody
    see all

Anti-Cathepsin K antibody - Catalytic domain 画像

  • All lanes : Anti-Cathepsin K antibody - Catalytic domain (ab49893) at 1/1000 dilution

    Lane 1 : r-Human Cathepsin K at 0.04 µg
    Lane 2 : r-Human Cathepsin K at 0.02 µg
    Lane 3 : r-Human Cathepsin K at 0.01 µg
    Lane 4 : r-Human Cathepsin K at 0.004 µg
    Lane 5 : r-Human Cathepsin K at 0.002 µg


    Predicted band size : 37 kDa

プロトコール

Anti-Cathepsin K antibody - Catalytic domain (ab49893) 使用論文

ab49893 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"