製品の概要

  • 製品名Anti-Cathepsin K antibody
    Cathepsin K 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Cathepsin K
  • 特異性ab49892 recognizes all three forms of Cathepsin K (but does not see the 288 amino acid form as well as the other two forms, due to a partial deletion of the sequence). We have a range of domain specific antibodies for this target. For a full list please see all Cathepsin K antibodies.
  • アプリケーション適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide of Human Cathepsin K.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab49892 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use at an assay dependent dilution. PubMed: 20435685
WB 1/1000 - 1/5000. Predicted molecular weight: 37 kDa.

ターゲット情報

  • 機能Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation.
  • 組織特異性Predominantly expressed in osteclasts (bones).
  • 関連疾患Defects in CTSK are the cause of pycnodysostosis (PKND) [MIM:265800]. PKND is an autosomal recessive osteochondrodysplasia characterized by osteosclerosis and short stature.
  • 配列類似性Belongs to the peptidase C1 family.
  • 細胞内局在Lysosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cathepsin K antibody
    • Cathepsin O antibody
    • Cathepsin O1 antibody
    • Cathepsin O2 antibody
    • Cathepsin X antibody
    • CATK_HUMAN antibody
    • CTS02 antibody
    • Ctsk antibody
    • CTSO antibody
    • CTSO1 antibody
    • CTSO2 antibody
    • MGC23107 antibody
    • PKND antibody
    • PYCD antibody
    see all

Anti-Cathepsin K antibody 画像

  • All lanes : Anti-Cathepsin K antibody (ab49892) at 1/1000 dilution

    Lane 1 : HOS cell lysate
    Lane 2 : HOS cell lysate
    Lane 3 : HOS cell lysate


    Predicted band size : 37 kDa
    Observed band size : 26,46 kDa (why is the actual band size different from the predicted?)

プロトコール

Anti-Cathepsin K antibody (ab49892) 使用論文

This product has been referenced in:
  • Singh SR  et al. Can lineage-specific markers be identified to characterize mesenchyme-derived cell populations in the human airways? Am J Physiol Lung Cell Mol Physiol 299:L169-83 (2010). ICC/IF ; Human . Read more (PubMed: 20435685) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab49892.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"