製品の概要

  • 製品名
  • 製品の詳細
    Mouse polyclonal to Cathepsin E
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 18 - 397 of Human Cathepsin E

  • ポジティブ・コントロール
    • Stomach lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度
    Protein A purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab89414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.

ターゲット情報

  • 機能
    May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
  • 組織特異性
    Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes.
  • 配列類似性
    Belongs to the peptidase A1 family.
  • 翻訳後修飾
    Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide.
    Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57.
  • 細胞内局在
    Endosome. The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CATE antibody
    • CATE_HUMAN antibody
    • Cathepsin E antibody
    • Cathepsin E form II antibody
    • CTSE antibody
    • Erythrocyte membrane aspartic proteinase antibody
    • Slow moving proteinase antibody
    see all

画像

  • Anti-Cathepsin E antibody (ab89414) at 1 µg/ml + Human stomach lysate at 50 µg

    Predicted band size : 43 kDa
  • All lanes : Anti-Cathepsin E antibody (ab89414) at 1 µg/ml

    Lane 1 : Cathepsin E transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 43 kDa
    Observed band size : 43 kDa

プロトコール

参考文献

ab89414 has not yet been referenced specifically in any publications.

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