Anti-Cathepsin E 抗体 (ab89414)
Key features and details
- Mouse polyclonal to Cathepsin E
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Cathepsin E antibody
Cathepsin E 一次抗体 製品一覧 -
製品の詳細
Mouse polyclonal to Cathepsin E -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment, corresponding to amino acids 18 - 397 of Human Cathepsin E
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ポジティブ・コントロール
- Stomach lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab89414の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa. |
ターゲット情報
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機能
May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. -
組織特異性
Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes. -
配列類似性
Belongs to the peptidase A1 family. -
翻訳後修飾
Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide.
Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57. -
細胞内局在
Endosome. The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome. - Information by UniProt
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参照データベース
- Entrez Gene: 1510 Human
- Omim: 116890 Human
- SwissProt: P14091 Human
- Unigene: 644082 Human
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別名
- CATE antibody
- CATE_HUMAN antibody
- Cathepsin E antibody
see all
画像
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Anti-Cathepsin E antibody (ab89414) at 1 µg/ml + Human stomach lysate at 50 µg
Predicted band size: 43 kDa -
All lanes : Anti-Cathepsin E antibody (ab89414) at 1 µg/ml
Lane 1 : Cathepsin E transfected 293T cell lysate
Lane 2 : Non-transfected lysate
Lysates/proteins at 25 µg per lane.
Predicted band size: 43 kDa
Observed band size: 43 kDa
データシートおよび資料
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Datasheet download
参考文献 (0)
ab89414 は論文での使用が確認できていません。