製品の概要

  • 製品名Anti-Caspr2 antibody
    Caspr2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Caspr2
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the center region of Human Caspr2 (NP_054860.1).

  • ポジティブ・コントロール
    • CEM cell line lysates

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)This antibody is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab93228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: 1/1000.
    WB: 1/100 - 1/500. Predicted molecular weight: 148 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the juxtaparanodal region of the axo-glial junction.
    • 組織特異性Predominantly expressed in nervous system.
    • 関連疾患Defects in CNTNAP2 are the cause of cortical dysplasia-focal epilepsy syndrome (CDFES) [MIM:610042]. Affected individuals manifest cortical dysplasia, focal epilepsy, relative macrocephaly, and diminished deep-tendon reflexes. Intractable focal seizures begin in early childhood, after which language regression, hyperactivity, impulsive and aggressive behavior, and mental retardation develop.
      Genetic variations in CNTNAP2 influences susceptibility to autism type 15 (AUTS15) [MIM:612100]. Autism is a neurodevelopmental disorder characterized by disturbance in language, perception and socialization. The disorder is classically defined by a triad of limited or absent verbal communication, a lack of reciprocal social interaction or responsiveness, and restricted, stereotypical, and ritualized patterns of interests and behavior.
      Note=A chromosomal aberration involving CNTNAP2 is found in a patient with autism spectrum disorder. Paracentric inversion 46,XY,inv(7)(q11.22;q35). The inversion breakpoints disrupt the genes AUTS2 and CNTNAP2.
    • 配列類似性Belongs to the neurexin family.
      Contains 2 EGF-like domains.
      Contains 1 F5/8 type C domain.
      Contains 1 fibrinogen C-terminal domain.
      Contains 4 laminin G-like domains.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AUTS15 antibody
      • CDFE antibody
      • Cell recognition molecule Caspr2 antibody
      • CNTNAP2 antibody
      • CNTP2 antibody
      • CNTP2_HUMAN antibody
      • Contactin-associated protein-like 2 antibody
      • Homolog of Drosophila neurexin IV antibody
      • NRXN4 antibody
      • PTHSL1 antibody
      see all

    Anti-Caspr2 antibody 画像

    • Anti-Caspr2 antibody (ab93228) at 1/100 dilution + CEM cell line lysates at 35 µg

      Predicted band size : 148 kDa

    Anti-Caspr2 antibody (ab93228) 使用論文

    ab93228 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab93228.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"