製品の概要

  • 製品名Anti-Caspase-7 antibody
    Caspase-7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Caspase-7
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to Human Caspase-7 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: P55210

  • ポジティブ・コントロール
    • Skeletal muscle cell lysate. Colon or skin tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab109705 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 34 kDa.
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-
    -Gly-217' bond. Overexpression promotes programmed cell death.
  • 組織特異性Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
  • 配列類似性Belongs to the peptidase C14A family.
  • 翻訳後修飾Cleavages by granzyme B or caspase-10 generate the two active subunits. Propeptide domains can also be cleaved efficiently by caspase-3. Active heterodimers between the small subunit of caspase-7 and the large subunit of caspase-3, and vice versa, also occur.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Apoptotic protease Mch-3 antibody
    • Apoptotic protease MCH3 antibody
    • CASP-7 antibody
    • CASP7 antibody
    • CASP7_HUMAN antibody
    • Caspase 7 antibody
    • Caspase 7 apoptosis related cysteine peptidase antibody
    • Caspase-7 subunit p11 antibody
    • Caspase7 antibody
    • CMH 1 antibody
    • CMH-1 antibody
    • CMH1 antibody
    • ICE LAP3 antibody
    • ICE-LAP3 antibody
    • ICE-like apoptotic protease 3 antibody
    • LICE2 antibody
    • MCH3 antibody
    see all

Anti-Caspase-7 antibody 画像

  • Lane 1 : Anti-Caspase-7 antibody (ab109705) at 0.5 µg/ml
    Lane 2 : Anti-Caspase-7 antibody (ab109705) at 1 µg/ml

    Lane 1 : Human skeletal muscle cell lysate
    Lane 2 : Human skeletal muscle cell lysate


    Predicted band size : 34 kDa
  • ab109705 at 5 µg/ml staining Caspase-7 in formalin-fixed, paraffin-embedded Human colon tissue.

  • ab109705 at 5 µg/ml staining Caspase-7 in formalin-fixed, paraffin-embedded Human skin tissue.

Anti-Caspase-7 antibody (ab109705) 使用論文

ab109705 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"