Goat polyclonal to Caspase 4
This antibody is expected to recognise all 3 isoforms of CASP4 (alpha, represented by NP_001216; gamma, NP-150649 and delta NP_150650).
Cow, Cat, Dog
Heart and brain lysates for Western Blot.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, 5mg/ml Tris, pH 7.3
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Immunogen affinity purified
This antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.3 - 2 µg/ml. Detects a band of approximately 40 kDa.
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves caspase-1.
Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.
Belongs to the peptidase C14A family.
Contains 1 CARD domain.
The two subunits are derived from the precursor sequence by an autocatalytic mechanism or by cleavage by Caspase-8.
Information by UniProt
Apoptotic cysteine protease Mih1/TX antibody
Western blot - Anti-Caspase 4 antibody (ab27485)
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