Anti-Casein Kinase 1 delta 抗体 (ab37971)

製品の概要

  • 製品名Anti-Casein Kinase 1 delta antibody
    Casein Kinase 1 delta 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Casein Kinase 1 delta
  • 特異性ab37971 recognizes Casein Kinase 1 delta.
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide, derived from C terminal within residues 336-352 of Casein Kinase 1 delta (Human).

  • ポジティブ・コントロール
    • HeLa cell lysate (WB), human breast carcinoma and human hepatocarcinoma tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab37971 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Detects a band of approximately 47 kDa.
ELISA 1/1000.
IHC-P 1/50 - 1/100.

ターゲット情報

  • 機能Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm.
  • 組織特異性Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. In blood, highly expressed in hemopoietic cells and mature granulocytes. Also found in monocytes and lymphocytes.
  • 関連疾患Defects in CSNK1D are a cause of familial advanced sleep-phase syndrome (FASPS) [MIM:604348]. FASPS is characterized by very early sleep onset and offset. Individuals are 'morning larks' with a 4 hours advance of the sleep, temperature and melatonin rhythms.
  • 配列類似性Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Autophosphorylated on serine and threonine residues.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Casein kinase I delta isoform antibody
    • Casein kinase I isoform delta antibody
    • CKI delta antibody
    • CKI-delta antibody
    • CKId antibody
    • CKIdelta antibody
    • CSNK 1D antibody
    • CSNK1D antibody
    • HCKID antibody
    • KC1D_HUMAN antibody
    • Protein kinase CK1 delta antibody
    see all

Anti-Casein Kinase 1 delta antibody 画像

  • Anti-Casein Kinase 1 delta antibody (ab37971) + HeLa cell lysate

    Secondary
    HRP-anti-rabbit

    Observed band size : 47 kDa (why is the actual band size different from the predicted?)
  • Formalin-fixed and paraffin-embedded human cancer tissue reacted with ab37971, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. HC = hepatocarcinoma.

Anti-Casein Kinase 1 delta antibody (ab37971) 使用論文

ab37971 has not yet been referenced specifically in any publications.

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