製品の概要

  • 製品名
    Anti-Casein Kinase 1 alpha antibody [AT2E2]
    Casein Kinase 1 alpha 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [AT2E2] to Casein Kinase 1 alpha
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length human protein Casein Kinase 1 alpha purified from E. coli (NP_001883)

  • ポジティブ・コントロール
    • HeLa and MCF7 cell lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/2000. Predicted molecular weight: 39 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
  • 配列類似性
    Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
    Contains 1 protein kinase domain.
  • 細胞内局在
    Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Nucleus speckle. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Casein kinase 1 alpha 1 antibody
    • Casein kinase I isoform alpha antibody
    • CK1 antibody
    • CK1A antibody
    • CKI alpha antibody
    • CKI-alpha antibody
    • CKIa antibody
    • Clock regulator kinase antibody
    • Csnk1a1 antibody
    • Down regulated in lung cancer antibody
    • HLCDGP1 antibody
    • KC1A_HUMAN antibody
    • PRO2975 antibody
    see all

画像

  • All lanes : Anti-Casein Kinase 1 alpha antibody [AT2E2] (ab88079) at 1/1000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : MCF7 cell lysate

    Lysates/proteins at 40 µg per lane.

    Secondary
    HRP conjugated goat anti-mouse IgG
    Developed using the ECL technique

    Predicted band size : 39 kDa
    Observed band size : 39 kDa

プロトコール

参考文献

This product has been referenced in:
  • Lin TC  et al. The nucleolar protein NIFK promotes cancer progression via CK1a/ß-catenin in metastasis and Ki-67-dependent cell proliferation. Elife 5:N/A (2016). WB . Read more (PubMed: 26984280) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab88079.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録