製品の概要

  • 製品名Carvedilol
  • 製品の詳細
    Potent β and α1 adrenoceptor antagonist
  • 生理活性の詳細Potent β and α1 adrenoceptor antagonist (Ki values are 0.81, 0.96 and 2.2 nM for β1, β2 and α1 adrenoceptors, respectively). Shows antihypertensive, antioxidant, antiapoptotic, anti-inflammatory and antifibrotic properties.
  • 精製度> 99%

製品の特性

    Carvedilol (ab120709) 使用論文

    This product has been referenced in:
    • Arozal W  et al. Carvedilol-Afforded Protection against Daunorubicin-Induced Cardiomyopathic Rats In Vivo: Effects on Cardiac Fibrosis and Hypertrophy. ISRN Pharmacol 2011:430549 (2011). Read more (PubMed: 22084713) »
    • Pönicke K  et al. Differential effects of bucindolol and carvedilol on noradenaline-induced hypertrophic response in ventricular cardiomyocytes of adult rats. J Pharmacol Exp Ther 301:71-6 (2002). Read more (PubMed: 11907159) »
    • Ruffolo RR  et al. The pharmacology of carvedilol. Eur J Clin Pharmacol 38 Suppl 2:S82-8 (1990). Read more (PubMed: 1974511) »

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