Anti-Cardiac Troponin T 抗体 [0.N.590] (ab33589)


  • 製品名Anti-Cardiac Troponin T antibody [0.N.590]
    Cardiac Troponin T 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [0.N.590] to Cardiac Troponin T
  • 特異性Recognizes the cardiac isoform of Troponin T (cTnT).
  • アプリケーション適用あり: WB, IHC-P, Electron Microscopy, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Rat, Rabbit, Chicken, Guinea pig, Dog, Human, Pig, Goldfish
    交差が予測される動物種: Sheep, Cat, Turkey, Zebrafish
  • 免疫原

    Synthetic peptide:


    (5' region of the cardiac gene exon 10),corresponding to Rabbit Cardiac Troponin T

  • エピトープTnT4R Epitope.
  • ポジティブ・コントロール
    • Cardiac muscle



Our Abpromise guarantee covers the use of ab33589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Electron Microscopy
  • 追加情報Electron Microscopy: Use at an assay dependent dilution.
    ICC/IF: Use at an assay dependent dilution.
    IHC-P: Use at a concentration of 1 - 2 µg/ml.
    WB: 1/1000. Detects a band of approximately 34 kDa (predicted molecular weight: 34 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • ��能Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
    • 組織特異性Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
    • 関連疾患Defects in TNNT2 are the cause of cardiomyopathy familial hypertrophic type 2 (CMH2) [MIM:115195]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death.
      Defects in TNNT2 are the cause of cardiomyopathy dilated type 1D (CMD1D) [MIM:601494]. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
      Defects in TNNT2 are the cause of cardiomyopathy familial restrictive type 3 (RCM3) [MIM:612422]. Restrictive cardiomyopathy is a heart disorder characterized by impaired filling of the ventricles with reduced diastolic volume, in the presence of normal or near normal wall thickness and systolic function.
    • 配列類似性Belongs to the troponin T family.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Cardiac muscle troponin T antibody
      • Cardiomyopathy dilated 1D (autosomal dominant) antibody
      • Cardiomyopathy hypertrophic 2 antibody
      • CMD1D antibody
      • CMH2 antibody
      • CMPD2 antibody
      • cTnT antibody
      • LVNC6 antibody
      • MGC3889 antibody
      • OTTHUMP00000033864 antibody
      • OTTHUMP00000033865 antibody
      • OTTHUMP00000033866 antibody
      • OTTHUMP00000033867 antibody
      • OTTHUMP00000033870 antibody
      • OTTHUMP00000218095 antibody
      • RCM3 antibody
      • TNNT 2 antibody
      • TNNT2 antibody
      • TNNT2_HUMAN antibody
      • TnTc antibody
      • Troponin T cardiac muscle antibody
      • Troponin T type 2 (cardiac) antibody
      • Troponin T type 2 cardiac antibody
      • Troponin T, cardiac muscle antibody
      • Troponin T2 cardiac antibody
      see all

    Anti-Cardiac Troponin T antibody [0.N.590] (ab33589) 使用論文

    This product has been referenced in:
    • Yin N  et al. Islet-1 promotes the cardiac-specific differentiation of mesenchymal stem cells through the regulation of histone acetylation. Int J Mol Med 33:1075-82 (2014). WB . Read more (PubMed: 24604334) »
    • Zamperone A  et al. Isolation and characterization of a spontaneously immortalized multipotent mesenchymal cell line derived from mouse subcutaneous adipose tissue. Stem Cells Dev 22:2873-84 (2013). Mouse . Read more (PubMed: 23777308) »

    See all 8 Publications for this product

    Product Wall

    Thank you for contacting us.

    The epitope sequence of antibody ab33589 has been updated.

    The epitope sequence information of ab998 and ab106076 is proprietary, we unfortunately are not able to disclose this information. These products...

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    Thank you for sending the sample and protocol details. I think your protocol is good and that the best option now is to replace the antibodies with different antibodies. If you have two in mind, please send the catalogue numbers. If not, I will be happ...

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    Thank you for bringing this to our attention. If I cannot offer a useful suggestion to improve your results, and if the antibodies are covered by our guarantee, I will send replacements.

    I will first need a few details of your experiment and...

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    Thank you for your call today. The cardiac troponin T antibody ab33589 should recognize the fetal chick isoform, as the immunogen is 100% homologous to a section of the fetal protein based on the SwissProt reference- http://www.uniprot.or...

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    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application Western blot
    Sample Mouse Tissue lysate - whole (heart, ventricular tissue)
    Specification heart, ventricular tissue
    Gel Running Conditions Reduced Denaturing (4~12%)
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 25°C

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    投稿 Feb 02 2008