PE Anti-CEACAM5 抗体 [CB30] (ab42796)
Key features and details
- PE Mouse monoclonal [CB30] to CEACAM5
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
製品の概要
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製品名
PE Anti-CEACAM5 antibody [CB30]
CEACAM5 一次抗体 製品一覧 -
製品の詳細
PE Mouse monoclonal [CB30] to CEACAM5 -
由来種
Mouse -
標識
PE. Ex: 488nm, Em: 575nm -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Human -
免疫原
Full length native protein (purified) corresponding to Human CEACAM5.
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特記事項
ab42796 is a heavily glycosylated GPI anchored protein capable of heterophilic and homophilic adhesion and may play a role in metastasis of cancer cells. It is found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
Preservative: 0.1% Sodium azide
Constituents: PBS, 0.5% BSA -
Concentration information loading...
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特記事項(精製)
ab42796 is a purified fraction from size exclusion chromatography. -
一次抗体 備考
ab42796 is a heavily glycosylated GPI anchored protein capable of heterophilic and homophilic adhesion and may play a role in metastasis of cancer cells. It is found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. -
ポリ/モノ
モノクローナル -
クローン名
CB30 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab42796の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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Flow Cyt |
Use at an assay dependent concentration.
10 ul is sufficient to label 0.1 - 1x10^6 leucocytes in 100 ul. ab91357 - Mouse monoclonal IgG1 is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use at an assay dependent concentration. 10 ul is sufficient to label 0.1 - 1x10^6 leucocytes in 100 ul. ab91357 - Mouse monoclonal IgG1 is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. -
組織特異性
Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. -
配列類似性
Belongs to the immunoglobulin superfamily. CEA family.
Contains 7 Ig-like (immunoglobulin-like) domains. -
翻訳後修飾
Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 1048 Human
- Omim: 114890 Human
- SwissProt: P06731 Human
- Unigene: 709196 Human
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別名
- Carcinoembryonic antigen antibody
- Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
- CD66e antibody
see all
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab42796 は 2 報の論文で使用されています。
- McNeil NE et al. Novel mouse model recapitulates genome and transcriptome alterations in human colorectal carcinomas. Genes Chromosomes Cancer 56:199-213 (2017). PubMed: 27750367
- Ray S et al. Establishment of human ultra-low passage colorectal cancer cell lines using spheroids from fresh surgical specimens suitable for in vitro and in vivo studies. J Cancer 3:196-206 (2012). Flow Cyt . PubMed: 22606209