Anti-Carcino Embryonic Antigen CEA 抗体 [C6G9] (ab11330)


  • 製品名Anti-Carcino Embryonic Antigen CEA antibody [C6G9]
    Carcino Embryonic Antigen CEA 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [C6G9] to Carcino Embryonic Antigen CEA
  • 特異性Monoclonal Anti-Human Carcinoembryonic Antigen (CEA) reacts specifically with human CEA (CD66e, 180 kDa) from several types of malignant tissues including colorectal, lung and breast tumors. It also stains medullary carcinomas of the thyroid. The product reacts strongly with the cell surface and cytoplasm of malignant glands in colorectal adenocarcinomas. A weak reactivity is seen with normal colon mucosa and occasionally with bile canalicular and pancreatic acinar cells, but not with other tested normal tissues including term placenta.
  • アプリケーション適用あり: Dot blot, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    CEA isolated from a human colon adenocarcinoma cell line.

  • 特記事項Storage in frost-free freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.



Our Abpromise guarantee covers the use of ab11330 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Dot blot
  • 追加情報Dot: 1/8000.
    IHC-P: 1/8000. Perform enzymatic antigen retrieval before commencing with IHC staining protocol.
    WB: 1/8000. Predicted molecular weight: 180 kDa.

    There is no cross reactivity with nonspecific cross-reacting antigen (NCA) present in granulocytes by immunoblotting, flow cytometry or immunohistochemical techniques.

    The antibody recognizes an epitope that is resistant to 30 minute oxidation by 1% sodium periodate solution in routine formalin-fixed, paraffin-embedded tissue sections. Enzymatic predigestion with proteolytic enzymes enhances immunohistochemical staining of formalinfixed, paraffin-embedded tissue sections with the antibody.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
    • 組織特異性Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
    • 配列類似性Belongs to the immunoglobulin superfamily. CEA family.
      Contains 7 Ig-like (immunoglobulin-like) domains.
    • 翻訳後修飾Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.
    • 細胞内局在Cell membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Carcinoembryonic antigen antibody
      • Carcinoembryonic antigen-related cell adhesion molecule 5 antibody
      • CD66e antibody
      • CEA antibody
      • Ceacam5 antibody
      • CEAM5_HUMAN antibody
      • DKFZp781M2392 antibody
      • Meconium antigen 100 antibody
      • OTTHUMP00000199032 antibody
      • OTTHUMP00000199033 antibody
      • OTTHUMP00000199034 antibody
      see all

    Anti-Carcino Embryonic Antigen CEA antibody [C6G9] (ab11330) 使用論文

    This product has been referenced in:
    • Guo X  et al. In vitro evaluation of cancer-specific NF-kappaB-CEA enhancer-promoter system for 5-fluorouracil prodrug gene therapy in colon cancer cell lines. Br J Cancer 97:745-54 (2007). WB ; Human . Read more (PubMed: 17687334) »

    See 1 Publication for this product

    Product Wall

    Thank you for your enquiry. For the following antibodies, epitope specificity is given per ISOBM classification and we have only following information: Ab10038 - Epitope specificity group IV, cross-reactive with NCA2. Ab10039 - Epitope specificity ...

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