Mouse monoclonal [26/5/1] to Carcino Embryonic Antigen CEA
特異性Ab26285 recognizes exclusively CEACAM5 transiently expressed on the cell surface of transfected BOSC cells. It can be used to distinguish CEACAM5 from all other CEACAM and probably all pregnancy specific glycoproteins molecules, namely CEACAM1 (BGP/CD66a), CEACAM3 (CGM1/CD66d), CEACAM4 (CGM7), CEACAM6 (NCA/CD66c), CEACAM7 (CGM2), CEACAM8 (CGM6/CD66b) and PSG1 (CD66f) based on its reactivity pattern with stable HeLa transfectants expressing individual CEA family members.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報ELISA: Use at an assay dependent dilution.
Flow Cyt: Use at an assay dependent dilution.
IF: Use at an assay dependent dilution.
IHC-Fr: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 77 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
機能Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.
組織特異性Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.
配列類似性Belongs to the immunoglobulin superfamily. CEA family. Contains 7 Ig-like (immunoglobulin-like) domains.
翻訳後修飾Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate.