製品の概要

  • 製品名Anti-CANT1 antibody
    CANT1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to CANT1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: ASQERYSEKD DERKGANLLL SASPDFGDIA VSHVGAVVPT HGFSSFKFIP NTDDQIIVAL KSEEDSGRVA SYIMAFTLDG RFLLPETKIG SVKYEGIEFI , corresponding to amino acids 302-401 of Human CANT1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.
    • 組織特異性Widely expressed.
    • 関連疾患Defects in CANT1 are the cause of Desbuquois dysplasia (DBQD) [MIM:251450]. A chondrodysplasia characterized by severe prenatal and postnatal growth retardation (less than -5 SD), joint laxity, short extremities, progressive scoliosis, round face, midface hypoplasia, prominent bulging eyes. The main radiologic features are short long bones with metaphyseal splay, a 'Swedish key' appearance of the proximal femur (exaggerated trochanter), and advance carpal and tarsal bone age. Two forms of Desbuquois dysplasia are distinguished on the basis of the presence (type 1) or absence (type 2) of characteristic hand anomalies: an extra ossification center distal to the second metacarpal, delta phalanx, bifid distal thumb phalanx, and phalangeal dislocations.
    • 配列類似性Belongs to the apyrase family.
    • 翻訳後修飾N-glycosylated.
    • 細胞内局在Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Processed form: Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Apyrase antibody
      • Apyrase homolog antibody
      • Ca2+ dependent endoplasmic reticulum nucleoside diphosphatase antibody
      • Calcium activated nucleotidase 1 antibody
      • CANT 1 antibody
      • CANT1 antibody
      • CANT1_HUMAN antibody
      • Putative MAPK activating protein PM09 antibody
      • Putative MAPK-activating protein PM09 antibody
      • Putative NF kappa B activating protein 107 antibody
      • Putative NF-kappa-B-activating protein 107 antibody
      • SCAN 1 antibody
      • SCAN-1 antibody
      • SHAPY antibody
      • Soluble Ca activated nucleotidase isozyme 1 antibody
      • Soluble calcium activated nucleotidase 1 antibody
      • Soluble calcium activated nucleotidase SCAN 1 antibody
      • Soluble calcium-activated nucleotidase 1 antibody
      see all

    Anti-CANT1 antibody 画像



    • Predicted band size : 45 kDa
      CANT1 antibody (ab57343) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    Anti-CANT1 antibody (ab57343) 使用論文

    ab57343 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57343.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"