Anti-Cannabinoid Receptor II 抗体 (ab54565)

製品の概要

  • 製品名Anti-Cannabinoid Receptor II antibody
    Cannabinoid Receptor II 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Cannabinoid Receptor II
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 302-360 of Human Cannabinoid Receptor II

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG1
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab54565 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
    • 組織特異性Preferentially expressed in cells of the immune system with higher expression in B cells and NK cells (at protein level). Expressed in skin in suprabasal layers and hair follicles (at protein level). Highly expressed in tonsil and to a lower extent in spleen, peripheral blood mononuclear cells, and thymus. PubMed:14657172 could not detect expression in normal brain. Expressed in brain by perivascular microglial cells and dorsal root glanglion sensory neurons (at protein level).
    • 配列類似性Belongs to the G-protein coupled receptor 1 family.
    • 翻訳後修飾Constitutively phosphorylated on Ser-352; phosphorylation increases cell internalization and desensitizes the receptor.
    • 細胞内局在Cell membrane. Cell projection > dendrite. Perikaryon. Localizes to apical dendrite of pyramidal neurons.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Cannabinoid receptor 2 antibody
      • Cannabinoid receptor 2 macrophage antibody
      • CB 2 antibody
      • CB-2 antibody
      • CB2 antibody
      • CNR2 antibody
      • CNR2_HUMAN antibody
      • CNRII antibody
      • CX 5 antibody
      • CX5 antibody
      • hCB2 antibody
      • testis-dominant CNR2 isoform CB2 antibody
      see all

    Anti-Cannabinoid Receptor II antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab54565 Cannabinoid Receptor II antibody at 1ug/ml. Predicted band size of immunogen is 32 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-Cannabinoid Receptor II antibody (ab54565) 使用論文

    ab54565 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab54565.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"