Anti-CAMKK2 抗体 - C-terminal (ab70909)


  • 製品名Anti-CAMKK2 antibody - C-terminal
    CAMKK2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CAMKK2 - C-terminal
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide from the C-terminal region of human CAMKK2 conjugated to KLH.

  • ポジティブ・コントロール
    • 293 cell lysates transiently transfected with the CAMKK2 gene. Human brain tissue.



Our Abpromise guarantee covers the use of ab70909 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Detects a band of approximately 65 kDa (predicted molecular weight: 65 kDa).
ELISA 1/1000.
IHC-P 1/50.


  • 機能Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Seems to be involved in hippocampal activation of CREB1.
  • 組織特異性Ubiquitously expressed with higher levels in the brain. Intermediate levels are detected in spleen, prostate, thyroid and leukocytes. The lowest level is in lung.
  • 配列類似性Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • ドメインThe autoinhibitory domain overlaps with the calmodulin binding region and may be involved in intrasteric autoinhibition.
    The RP domain (arginine/proline-rich) is involved in the recognition of CAMKI and CAMK4 as substrates.
  • 翻訳後修飾Autophosphorylated.
  • 細胞内局在Cytoplasm.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Calcium/calmodulin dependent protein kinase beta antibody
    • Calcium/calmodulin dependent protein kinase kinase 2 antibody
    • Calcium/calmodulin dependent protein kinase kinase 2 beta antibody
    • Calcium/calmodulin dependent protein kinase kinase beta antibody
    • Calcium/calmodulin-dependent protein kinase kinase 2 antibody
    • Calcium/calmodulin-dependent protein kinase kinase beta antibody
    • CaM kinase kinase beta antibody
    • CaM KK beta antibody
    • CaM-kinase kinase 2 antibody
    • CaM-kinase kinase beta antibody
    • CaM-KK 2 antibody
    • CaM-KK beta antibody
    • CaMKK 2 antibody
    • CAMKK antibody
    • CaMKK beta antibody
    • CAMKK beta protein antibody
    • Camkk2 antibody
    • CAMKKB antibody
    • KKCC2_HUMAN antibody
    see all

Anti-CAMKK2 antibody - C-terminal 画像

  • All lanes : Anti-CAMKK2 antibody - C-terminal (ab70909) at 1/50 dilution

    Lane 1 : Nontransfected 293 cell lysate
    Lane 2 : 293 cell lysate transiently transfected with the CAMKK2 gene

    Lysates/proteins at 2 µg per lane.

    Predicted band size : 65 kDa
    Observed band size : 65 kDa
    Additional bands at : 62 kDa. We are unsure as to the identity of these extra bands.
  • ab70909, at 1/50 dilution, staining CAMKK2 in human brain tissue by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue followed by a peroxidase-conjugated secondary antibody and DAB staining.

Anti-CAMKK2 antibody - C-terminal (ab70909) 使用論文

ab70909 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample Rat Tissue sections (spinal cord)
Specification spinal cord
Fixative Paraformaldehyde
Permeabilization No

Dr. Karine Thibault

Verified customer

投稿 Dec 14 2010