製品の概要

  • 製品名Anti-CaMKK antibody - N-terminal
    CaMKK 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CaMKK - N-terminal
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the N terminal region of human CaMKK

  • ポジティブ・コントロール
    • Mouse cerebellum tissue lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab76534 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).
ELISA 1/1000.

ターゲット情報

  • 機能Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.
  • 配列類似性Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • ドメインThe autoinhibitory domain overlaps with the calmodulin binding region and may be involved in intrasteric autoinhibition.
    The RP domain (arginine/proline-rich) is involved in the recognition of CAMKI and CAMK4 as substrates.
  • 翻訳後修飾Appears to be autophosphorylated in a Ca(2+)/calmodulin-dependent manner. Phosphorylated at multiple sites by PRCAKA/PKA. Phosphorylation of Ser-458 is blocked upon binding to Ca(2+)/calmodulin. In vitro, phosphorylated by CAMK1 and CAMK4.
  • 細胞内局在Cytoplasm. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Ca2+/calmodulin-dependent protein kinase kinase alpha antibody
    • Calcium/calmodulin dependent protein kinase kinase antibody
    • Calcium/calmodulin dependent protein kinase kinase 1 alpha antibody
    • Calcium/calmodulin dependent protein kinase kinase 1 antibody
    • Calcium/calmodulin dependent protein kinase kinase alpha antibody
    • Calcium/calmodulin-dependent protein kinase kinase 1 antibody
    • Calcium/calmodulin-dependent protein kinase kinase alpha antibody
    • CaM kinase kinase alpha antibody
    • CaM-kinase IV kinase antibody
    • CaM-kinase kinase 1 antibody
    • CaM-kinase kinase alpha antibody
    • CaM-KK 1 antibody
    • CaM-KK alpha antibody
    • CaMKK 1 antibody
    • CaMKK alpha antibody
    • CAMKK alpha protein antibody
    • CaMKK antibody
    • Camkk1 antibody
    • CAMKKA antibody
    • DKFZp761M0423 antibody
    • KKCC1_HUMAN antibody
    • MGC34095 antibody
    • OTTMUSP00000006419 antibody
    see all

Anti-CaMKK antibody - N-terminal 画像

  • Anti-CaMKK antibody - N-terminal (ab76534) at 1/50 dilution + mouse cerebellum tissue lysates at 35 µg

    Predicted band size : 56 kDa
    Observed band size : 56 kDa

Anti-CaMKK antibody - N-terminal (ab76534) 使用論文

ab76534 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab76534.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"