製品の概要

  • 製品名Anti-CaMKK antibody
    CaMKK 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CaMKK
  • 特異性This antibody is specific for CaMKK alpha form.
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide: GEGG KSPELPGVQE DEAAS, corresponding to C terminal amino acids 487-505 of Human CaMKK alpha.

  • ポジティブ・コントロール
    • Brain tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab40123 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/50 for 30 minutes at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.
    • 配列類似性Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
      Contains 1 protein kinase domain.
    • ドメインThe autoinhibitory domain overlaps with the calmodulin binding region and may be involved in intrasteric autoinhibition.
      The RP domain (arginine/proline-rich) is involved in the recognition of CAMKI and CAMK4 as substrates.
    • 翻訳後修飾Appears to be autophosphorylated in a Ca(2+)/calmodulin-dependent manner. Phosphorylated at multiple sites by PRCAKA/PKA. Phosphorylation of Ser-458 is blocked upon binding to Ca(2+)/calmodulin. In vitro, phosphorylated by CAMK1 and CAMK4.
    • 細胞内局在Cytoplasm. Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Ca2+/calmodulin-dependent protein kinase kinase alpha antibody
      • Calcium/calmodulin dependent protein kinase kinase antibody
      • Calcium/calmodulin dependent protein kinase kinase 1 alpha antibody
      • Calcium/calmodulin dependent protein kinase kinase 1 antibody
      • Calcium/calmodulin dependent protein kinase kinase alpha antibody
      • Calcium/calmodulin-dependent protein kinase kinase 1 antibody
      • Calcium/calmodulin-dependent protein kinase kinase alpha antibody
      • CaM kinase kinase alpha antibody
      • CaM-kinase IV kinase antibody
      • CaM-kinase kinase 1 antibody
      • CaM-kinase kinase alpha antibody
      • CaM-KK 1 antibody
      • CaM-KK alpha antibody
      • CaMKK 1 antibody
      • CaMKK alpha antibody
      • CAMKK alpha protein antibody
      • CaMKK antibody
      • Camkk1 antibody
      • CAMKKA antibody
      • DKFZp761M0423 antibody
      • KKCC1_HUMAN antibody
      • MGC34095 antibody
      • OTTMUSP00000006419 antibody
      see all

    Anti-CaMKK antibody 画像

    • ab40123 at a 1:50 dilution staining CaMKK in human brain tissue.

    Anti-CaMKK antibody (ab40123) 使用論文

    ab40123 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab40123.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"