製品の概要

製品の詳細

  • 由来Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab5859 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Liquid
  • 備考


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and mouse CaM-KIV, catalog ab3557. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

関連情報

  • 別名
    • Brain Ca(2+) calmodulin dependent protein kinase type 4
    • Brain Ca(2+) calmodulin dependent protein kinase type IV
    • Brain Ca++-calmodulin dependent protein kinase type IV
    • Calcium / calmodulin dependent protein kinase type 4 catalytic chain
    • Calcium / calmodulin dependent protein kinase type IV catalytic chain
    • Calcium/calmodulin dependent protein kinase IV
    • Calcium/calmodulin dependent protein kinase type IV
    • Calcium/calmodulin-dependent protein kinase type IV
    • CAM kinase 4
    • CAM kinase GR
    • CAM kinase IV
    • CAM kinase-GR
    • CaMK 4
    • CAMK GR
    • CaMK IV
    • Camk4
    • CaMKGR
    • IV
    • KCC4_HUMAN
    • MGC36771
    see all
  • 機能Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May be involved in transcriptional regulation. May be involved in regulation of microtubule dynamics. In vitro, phosphorylates CREB1, CREBBP, PRM2, MEF2A, MEF2D and STMN1/OP18. May be involved in spermatogenesis. May play a role in the consolidation/retention of hippocampus-dependent long-term memory.
  • 組織特異性Expressed in epithelial ovarian cancer tissue.
  • 配列類似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • 翻訳後修飾Autophosphorylated and phosphorylated by CAMKK1 and CAMKK2 (By similarity). Dephosphorylated by serine/threonine protein phosphatase 2A, probably on Thr-200.
  • 細胞内局在Cytoplasm. Nucleus. Substantial localization in certain neuronal nuclei. In spermatids associated with chromatin and nuclear matrix.
  • Information by UniProt

CAMKIV peptide (ab5859) 使用論文

ab5859 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab5859.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"