製品の概要

  • 製品名
  • 製品の詳細
    Goat polyclonal to CAMK1D
  • 特異性
    This antibody is expected to recognize isoform 1 of CAMK1D (NP_065130.1)
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Chimpanzee
  • 免疫原

    Synthetic peptide:

    ASQKDCAYVAKPES

    , corresponding to C terminal amino acids 342 - 355 of Human CAMK1D (NP_065130.1)

  • ポジティブ・コントロール
    • Human liver lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab81976 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報
    Peptide ELISA: antibody detection limit dilution 1/4000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. May regulate calcium-mediated granulocyte function. May play a role in apoptosis of erythroleukemia cells. Activates MAP kinase MAPK3 (By similarity). In vitro, phosphorylates transcription factor CREM isoform Beta and probably CREB1.
    • 組織特異性
      Broadly expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes.
    • 配列類似性
      Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
      Contains 1 protein kinase domain.
    • ドメイン
      The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
    • 細胞内局在
      Cytoplasm. Nucleus. Predominantly cytoplasmic (Probable). Also nuclear upon activation.
    • Information by UniProt
    • 参照データベース
    • 別名
      • A630059D12Rik antibody
      • Calcium/calmodulin dependent protein kinase ID antibody
      • Calcium/calmodulin dependent protein kinase type 1D antibody
      • Calcium/calmodulin-dependent protein kinase I-delta antibody
      • Calcium/calmodulin-dependent protein kinase type 1D antibody
      • CaM K1 antibody
      • CaM KI delta antibody
      • CaM kinase I delta antibody
      • CaM kinase ID antibody
      • CaM-KI delta antibody
      • CAMK 1D antibody
      • CAMK1D antibody
      • CaMKI delta antibody
      • CamKI like protein kinase antibody
      • CamKI-like protein kinase antibody
      • CaMKID antibody
      • CKLiK antibody
      • E030025C11Rik antibody
      • KCC1D_HUMAN antibody
      • OTTHUMP00000019119 antibody
      • OTTHUMP00000019120 antibody
      • OTTHUMP00000045030 antibody
      • RP11 462F15.1 antibody
      see all

    画像

    • Anti-CAMK1D antibody (ab81976) at 0.5 µg/ml + Human liver lysate in RIPA buffer at 35 µg

      Predicted band size : 43 kDa
      Observed band size : 43 kDa

    プロトコール

    参考文献

    ab81976 has not yet been referenced specifically in any publications.

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