製品の概要

  • 製品名
  • 製品の詳細
    Mouse polyclonal to Calumenin
  • アプリケーション
    適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length Calumenin protein (NP_001210) (Human)

  • ポジティブ・コントロール
    • Calumenin transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab72571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent dilution. PubMed: 21305022
WB 1/500 - 1/1000. Predicted molecular weight: 37 kDa.

ターゲット情報

  • 機能
    Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.
  • 組織特異性
    Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
  • 配列類似性
    Belongs to the CREC family.
    Contains 6 EF-hand domains.
  • 細胞内局在
    Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CALU antibody
    • CALU_HUMAN antibody
    • Calumenin 1 antibody
    • Calumenin 2 antibody
    • Calumenin antibody
    • Crocalbin antibody
    • crocalbin-like protein antibody
    • FLJ90608 antibody
    • IEF SSP 9302 antibody
    • multiple EF-hand protein antibody
    • OTTHUMP00000212712 antibody
    • OTTHUMP00000212713 antibody
    • OTTHUMP00000212714 antibody
    • OTTHUMP00000212715 antibody
    see all

画像

  • All lanes : Anti-Calumenin antibody (ab72571) at 1/500 dilution

    Lane 1 : Calumenin transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 37 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

参考文献

This product has been referenced in:
  • Gharesi-Fard B  et al. Alteration in the Expression of Proteins in Unexplained Recurrent Pregnancy Loss Compared with in the Normal Placenta. J Reprod Dev N/A:N/A (2014). WB ; Human . Read more (PubMed: 24621454) »
  • Voisin SN  et al. Identification of novel molecular targets for endometrial cancer using a drill-down LC-MS/MS approach with iTRAQ. PLoS One 6:e16352 (2011). WB, IHC-P ; Human . Read more (PubMed: 21305022) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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