製品の概要

  • 製品名Anti-Calsequestrin 2 antibody
    Calsequestrin 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Calsequestrin 2
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Cow
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 124-398 of Human Calsequestrin 2.

  • ポジティブ・コントロール
    • H1299 cells lysate and Cal27 xenograft

法規制情報

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab96387 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500. Antigen retrieval is not essential but may optimise staining.
WB 1/500 - 1/3000. Predicted molecular weight: 46 kDa.

ターゲット情報

  • 機能Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium.
  • 関連疾患Defects in CASQ2 are the cause of catecholaminergic polymorphic ventricular tachycardia type 2 (CPVT2) [MIM:611938]; also known as stress-induced polymorphic ventricular tachycardia (VTSIP). CPVT2 is an autosomal recessive form of arrhythmogenic disorder characterized by stress-induced, bidirectional ventricular tachycardia that may degenerate into cardiac arrest and cause sudden death.
  • 配列類似性Belongs to the calsequestrin family.
  • 細胞内局在Sarcoplasmic reticulum lumen. This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AA033488 antibody
    • AW146219 antibody
    • Calsequestrin 2 (cardiac muscle) antibody
    • Calsequestrin 2 fast twitch cardiac muscle antibody
    • Calsequestrin antibody
    • Calsequestrin cardiac muscle isoform antibody
    • Calsequestrin fast twitch cardiac muscle antibody
    • Calsequestrin-2 antibody
    • Calsequestrin2 antibody
    • cardCSQ antibody
    • Cardiac calsequestrin 2 antibody
    • cardiac muscle isoform antibody
    • CASQ 2 antibody
    • CASQ2 antibody
    • CASQ2_HUMAN antibody
    • cCSQ antibody
    • ESTM52 antibody
    • FLJ26321 antibody
    • FLJ93514 antibody
    • PDIB2 antibody
    see all

Anti-Calsequestrin 2 antibody 画像

  • Anti-Calsequestrin 2 antibody (ab96387) at 1/1000 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 46 kDa
  • Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using ab96387 at 1:500 dilution.

Anti-Calsequestrin 2 antibody (ab96387) 使用論文

ab96387 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab96387.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"