製品の概要

  • 製品名Anti-Calsequestrin 2 antibody
    Calsequestrin 2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to Calsequestrin 2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 20-400 of Human Calsequestrin 2

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab54858 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. Binds 40 to 50 moles of calcium.
    • 関連疾患Defects in CASQ2 are the cause of catecholaminergic polymorphic ventricular tachycardia type 2 (CPVT2) [MIM:611938]; also known as stress-induced polymorphic ventricular tachycardia (VTSIP). CPVT2 is an autosomal recessive form of arrhythmogenic disorder characterized by stress-induced, bidirectional ventricular tachycardia that may degenerate into cardiac arrest and cause sudden death.
    • 配列類似性Belongs to the calsequestrin family.
    • 細胞内局在Sarcoplasmic reticulum lumen. This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of cardiac and slow skeletal muscle cells.
    • Information by UniProt
    • 参照データベース
    • 別名
      • AA033488 antibody
      • AW146219 antibody
      • Calsequestrin 2 (cardiac muscle) antibody
      • Calsequestrin 2 fast twitch cardiac muscle antibody
      • Calsequestrin antibody
      • Calsequestrin cardiac muscle isoform antibody
      • Calsequestrin fast twitch cardiac muscle antibody
      • Calsequestrin-2 antibody
      • Calsequestrin2 antibody
      • cardCSQ antibody
      • Cardiac calsequestrin 2 antibody
      • cardiac muscle isoform antibody
      • CASQ 2 antibody
      • CASQ2 antibody
      • CASQ2_HUMAN antibody
      • cCSQ antibody
      • ESTM52 antibody
      • FLJ26321 antibody
      • FLJ93514 antibody
      • PDIB2 antibody
      see all

    Anti-Calsequestrin 2 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab54858 Calsequestrin 2 antibody at 1ug/ml. Predicted band size of immunogen is 68 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Anti-Calsequestrin 2 antibody (ab54858) 使用論文

    ab54858 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab54858.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"