製品の概要

  • 製品名
    Calpeptin
  • 製品の詳細
    Potent, cell-permeable calpain inhibitor
  • 生理活性の詳細
    Potent, cell-permeable calpain inhibitor, a Ca2+-dependent protease. Ki values are 34 and 52 nM for μ- and m-calpains, respectively. Demonstrates neuroprotective effects suggesting ability to cross the blood-brain barrier.
  • 精製度
    > 98%

製品の特性

参考文献

This product has been referenced in:
  • Smith AW  et al. Calpain inhibition attenuates apoptosis of retinal ganglion cells in acute optic neuritis. Invest Ophthalmol Vis Sci 52:4935-41 (2011). Read more (PubMed: 21613375) »
  • Rodríguez-Agudo D  et al. Rat histidine decarboxylase is a substrate for m-calpain in vitro. Biochem Biophys Res Commun 271:777-81 (2000). Read more (PubMed: 10814538) »
  • Tsujinaka T  et al. Synthesis of a new cell penetrating calpain inhibitor (calpeptin). Biochem Biophys Res Commun 153:1201-8 (1988). Read more (PubMed: 2839170) »

See 1 Publication for this product

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