Anti-Calpain S1 抗体 [28F3] (Biotin) (ab78565)


  • 製品名Anti-Calpain S1 antibody [28F3] (Biotin)
    Calpain S1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [28F3] to Calpain S1 (Biotin)
  • 標識Biotin
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Cow, Human
    非交差種: Mouse, Rat
  • 免疫原

    Human calpain from placenta

  • ポジティブ・コントロール
    • Normal human fibroblast; A431 and Madin-Darby bovine kidney cells (MDBK) lysates.
  • 特記事項This product was used in Hornberger W et al.,(2012) Novel approaches in label-free kinetic detection of small molecule ligand binding to receptor proteins using SAW (surface acoustic wave) technology. Poster Presented at Miptec Congress 2012



Our Abpromise guarantee covers the use of ab78565 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/5000. Detects a band of approximately 30 kDa (predicted molecular weight: 30 kDa).
IP Use at an assay dependent dilution.


  • 機能Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
  • 配列類似性Contains 5 EF-hand domains.
  • ドメインThe contact of the 5th EF-hand domain from each monomer allows the formation of the homodimer and also appears to mediate the contact between the large catalytic subunit and small regulatory subunit for the formation of the heterodimer.
    EF-hand domains are paired. EF-hand 1 is paired with EF-hand 2 and EF-hand 3 is paired with EF-hand 4. The fifth EF-hand domain, left unpaired, does not bind the calcium but is responsible of the dimerization by EF-embrace. The first four EF-hand domains bind calcium, however it is not sure if the binding of EF-hand 4 to calcium is physiologically relevant.
  • 細胞内局在Cytoplasm. Cell membrane. Translocates to the plasma membrane upon calcium binding.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 30K antibody
    • Calcium activated neutral proteinase antibody
    • Calcium activated neutral proteinase small subunit antibody
    • Calcium dependent protease small subunit 1 antibody
    • Calcium dependent protease small subunit antibody
    • Calcium-activated neutral proteinase small subunit antibody
    • Calcium-dependent protease small subunit 1 antibody
    • Calcium-dependent protease small subunit antibody
    • Calpain 4 antibody
    • Calpain 4 small subunit (30K) antibody
    • Calpain 4 small subunit antibody
    • Calpain regulatory subunit antibody
    • Calpain small polypeptide antibody
    • Calpain small subunit 1 antibody
    • Calpain4 antibody
    • CalpainS1 antibody
    • CANP antibody
    • CANP small subunit antibody
    • CANPS antibody
    • CAPN 4 antibody
    • CAPN S1 antibody
    • CAPN4 antibody
    • CAPNS 1 antibody
    • CAPNS antibody
    • Capns1 antibody
    • CDPS antibody
    • CPNS1_HUMAN antibody
    • CSS 1 antibody
    • CSS1 antibody
    see all

Anti-Calpain S1 antibody [28F3] (Biotin) (ab78565) 使用論文

ab78565 has not yet been referenced specifically in any publications.

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