製品の概要

  • 製品名
    Anti-Calpain 4 antibody
  • 製品の詳細
    Rabbit polyclonal to Calpain 4
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide derived from the internal region of Human Calpain 4

  • ポジティブ・コントロール
    • Human breast tissue

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.1% Sodium Azide
    Constituents: BSA, 10mM PBS, pH 7.4
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab93959 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性
      Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes.Calpain 4 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
    • 細胞内局在
      Cytoplasm. Cell membrane. Note: Translocates to the plasma membrane upon calcium binding
    • 参照データベース
    • 別名
      • 30K antibody
      • Calcium activated neutral proteinase antibody
      • Calcium activated neutral proteinase small subunit antibody
      • Calcium dependent protease small subunit 1 antibody
      • Calcium dependent protease small subunit antibody
      • Calpain 4 small subunit (30K) antibody
      • Calpain regulatory subunit antibody
      • Calpain small polypeptide antibody
      • Calpain small subunit 1 antibody
      • Calpain4 antibody
      • CANP antibody
      • CANP small subunit antibody
      • CANPS antibody
      • CAPN4 antibody
      • CAPNS 1 antibody
      • CAPNS1 antibody
      • CDPS antibody
      • CSS1 antibody
      see all

    画像

    • ab93959 at 1/100 dilution, staining Calpain 4 in formalin-fixed, paraffin-embedded Human breast tissue.

    プロトコール

    参考文献

    This product has been referenced in:
    • Liu T  et al. Calpastatin is regulated by protein never in mitosis gene A interacting-1 (PIN1) in endothelial cells. Biochem Biophys Res Commun 414:581-6 (2011). Read more (PubMed: 21982763) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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