製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to CALHM1
  • 特異性
    This antibody is predicted to not crossreact with CALHM2 or CALHM3.
  • アプリケーション
    適用あり: ICC/IF, WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to 17 amino acids near the amino terminus of Human CALHM1 (NP_001001412).

  • ポジティブ・コントロール
    • Rat liver tissue lysate; Rat liver tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
IHC-P Use a concentration of 5 µg/ml.

ターゲット情報

  • 機能
    May be a pore-forming ion channel. Controls cytosolic Ca(2+) permeability and cytosolic Ca(2+) concentration. Controls amyloid precursor protein (APP) proteolysis and aggregated amyloid-beta (Abeta) peptides levels in a Ca(2+) dependent manner.
  • 組織特異性
    Predominantly expressed in adult brain. Detected also in retinoic acid-differentiated SH-SY5Y cells.
  • 配列類似性
    Belongs to the FAM26 family.
  • 細胞内局在
    Cell membrane. Endoplasmic reticulum membrane. Colocalizes with HSPA5 at the endoplasmic reticulum.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CAHM1_HUMAN antibody
    • Calcium homeostasis modulator 1 antibody
    • Calcium homeostasis modulator protein 1 antibody
    • CALHM1 antibody
    • FAM26C antibody
    • Family with sequence similarity 26, member C antibody
    • MGC39514 antibody
    • MGC39617 antibody
    • OTTHUMP00000020413 antibody
    • Protein FAM26C antibody
    see all

画像

  • Lane 1 : Anti-CALHM1 antibody (ab106561) at 1 µg/ml
    Lane 2 : Anti-CALHM1 antibody (ab106561) at 2 µg/ml

    Lane 1 : Rat liver tissue lysate
    Lane 2 : Rat liver tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 38 kDa
  • Immunohistochemical analysis of CALHM1 in paraffin embedded Rat liver tissue, using ab106561 at 5 µg/ml.
  • Immunofluorescence of CALHM1 in Rat Liver cells using ab106561 at 20 ug/ml.

参考文献

ab106561 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab106561.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録