Anti-Calcium-independent Phospholipase A2 抗体 (ab104416)

製品の概要

  • 製品名Anti-Calcium-independent Phospholipase A2 antibody
    Calcium-independent Phospholipase A2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Calcium-independent Phospholipase A2
  • 特異性Reactive against mammalian transfected lysate.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Full length Human protein (NP_001004426.1)

  • ポジティブ・コントロール
    • Human kidney tissue lysate, Mouse kidney tissue lysate, Transfected 293T cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab104416 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 90 kDa.

ターゲット情報

  • 機能Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods.
    Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
  • 組織特異性Four different transcripts were found to be expressed in a distinct tissue distribution.
  • 関連疾患Neurodegeneration with brain iron accumulation 2B
    Neurodegeneration with brain iron accumulation 2A
    Parkinson disease 14
  • 配列類似性Contains 7 ANK repeats.
    Contains 1 patatin domain.
  • 細胞内局在Cytoplasm and Membrane. Recruited to the membrane-enriched pseudopod upon MCP1/CCL2 stimulation in monocytes.
  • Information by UniProt
  • 参照データベース
  • 製品の状態The isoform LH-iPLA2 is located at the membrane. The isoform SH-iPLA2 is cytoplasmic.
  • 別名
    • 85 kDa calcium independent phospholipase A2 antibody
    • 85/88 kDa calcium-independent phospholipase A2 antibody
    • BB112799 antibody
    • CaI PLA2 antibody
    • CaI-PLA2 antibody
    • CaIPLA2 antibody
    • Calcium independent phospholipase A2 antibody
    • CTA-228A.2 antibody
    • Cytosolic calcium independent phospholipase A2 antibody
    • EC 3.1.1.4 antibody
    • Group VI phospholipase A2 antibody
    • Group VI, A antibody
    • GVI antibody
    • GVI PLA2 antibody
    • INAD1 antibody
    • Intracellular membrane associated calcium independent phospholipase A2 beta antibody
    • Intracellular membrane-associated calcium-independent phospholipase A2 beta antibody
    • iPLA(2)beta antibody
    • iPLA2 beta antibody
    • iPLA2-beta antibody
    • IPLA2-VIA antibody
    • iPLA2beta antibody
    • NBIA2 antibody
    • NBIA2A antibody
    • NBIA2B antibody
    • Neurodegeneration with brain iron accumulation 2 antibody
    • OTTHUMP00000199457 antibody
    • PARK14 antibody
    • Patatin like phospholipase domain containing 9 antibody
    • Patatin like phospholipase domain containing protein 9 antibody
    • Patatin-like phospholipase domain-containing protein 9 antibody
    • Phospholipase A2 calcium independent antibody
    • Phospholipase A2 calcium independent group VI A antibody
    • Phospholipase A2 group VI antibody
    • Phospholipase A2 group VI cytosolic calcium independent antibody
    • Phospholipase A2, group VI (cytosolic, calcium independent) antibody
    • PLA2 antibody
    • PLA2G6 antibody
    • PLPL9_HUMAN antibody
    • PNPLA9 antibody
    see all

Anti-Calcium-independent Phospholipase A2 antibody 画像

  • Anti-Calcium-independent Phospholipase A2 antibody (ab104416) at 1 µg/ml + Human kidney tissue lysate at 50 µg

    Predicted band size : 90 kDa
  • Anti-Calcium-independent Phospholipase A2 antibody (ab104416) at 1 µg/ml + Mouse kidney tissue lysate at 50 µg

    Predicted band size : 90 kDa
  • All lanes : Anti-Calcium-independent Phospholipase A2 antibody (ab104416) at 1 µg/ml

    Lane 1 : Calcium-independent Phospholipase A2 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 90 kDa
    Observed band size : 84 kDa (why is the actual band size different from the predicted?)

Anti-Calcium-independent Phospholipase A2 antibody (ab104416) 使用論文

ab104416 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab104416.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"