Anti-Calcium channel L type DHPR alpha 2 subunit 抗体 (ab42586)

製品の概要

  • 製品名
    Anti-Calcium channel L type DHPR alpha 2 subunit antibody
    Calcium channel L type DHPR alpha 2 subunit 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Calcium channel L type DHPR alpha 2 subunit
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Chicken, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region of Human CACNA2D1 : PKSQEPVTLD FLDAELENDI KVEIRNKMID GESGEKTFRT LVKSQDERYI

  • ポジティブ・コントロール
    • Fetal muscle lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab42586 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.12 µg/ml. Predicted molecular weight: 123 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling.
  • 組織特異性
    Isoform 1 is expressed in skeletal muscle. Isoform 2 is expressed in the central nervous system. Isoform 2, isoform 4 and isoform 5 are expressed in neuroblastoma cells. Isoform 3, isoform 4 and isoform 5 are expressed in the aorta.
  • 配列類似性
    Belongs to the calcium channel subunit alpha-2/delta family.
    Contains 1 cache domain.
    Contains 1 VWFA domain.
  • ドメイン
    The MIDAS-like motif in the VWFA domain binds divalent metal cations and is required to promote trafficking of the alpha-1 (CACNA1) subunit to the plasma membrane by an integrin-like switch.
  • 翻訳後修飾
    Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CA2D1_HUMAN antibody
    • CACN A2 antibody
    • CACNA2 antibody
    • Cacna2d1 antibody
    • CACNL2A antibody
    • Calcium channel L type alpha 2 polypeptide antibody
    • Calcium channel voltage dependent alpha 2/delta subunit 1 antibody
    • CCHL2A antibody
    • Dihydropyridine receptor alpha 2 subunit antibody
    • Dihydropyridine sensitive L type calcium channel alpha 2/delta subunit antibody
    • Dihydropyridine sensitive L type calcium channel subunits alpha 2/delta antibody
    • L type calcium channel subunit alpha 2 antibody
    • MHS 3 antibody
    • MHS3 antibody
    • Voltage dependent calcium channel subunit alpha 2/delta 1 antibody
    • Voltage gated calcium channel subunit alpha 2/delta 1 antibody
    • Voltage-dependent calcium channel subunit delta-1 antibody
    • Voltage-gated calcium channel subunit alpha-2/delta-1 antibody
    see all

画像

  • Anti-Calcium channel L type DHPR alpha 2 subunit antibody (ab42586) at 0.12 µg/ml

    Predicted band size : 123 kDa

プロトコール

参考文献

ab42586 has not yet been referenced specifically in any publications.

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