Anti-Calcineurin A 抗体 (ab90540)
Key features and details
- Rabbit polyclonal to Calcineurin A
- Suitable for: WB
- Reacts with: Mouse, Rat
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Calcineurin A antibody
Calcineurin A 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Calcineurin A -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Rat -
免疫原
Synthetic peptide within the range of amino acids 250-300 of Human Calcineurin A
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab90540の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000. Predicted molecular weight: 59 kDa.
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特記事項 |
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WB
1/1000. Predicted molecular weight: 59 kDa. |
ターゲット情報
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機能
Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. -
配列類似性
Belongs to the PPP phosphatase family. PP-2B subfamily. -
細胞内局在
Nucleus. Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle. - Information by UniProt
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参照データベース
- Entrez Gene: 19055 Mouse
- Entrez Gene: 24674 Rat
- SwissProt: P63328 Mouse
- SwissProt: P63329 Rat
- Unigene: 331389 Mouse
- Unigene: 6866 Rat
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別名
- Alpha isoform formerly PPP2B antibody
- Calcineurin A alpha antibody
- Calcineurin A1 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (5)
ab90540 は 5 報の論文で使用されています。
- Li LY et al. Sacubitril/valsartan attenuates atrial electrical and structural remodelling in a rabbit model of atrial fibrillation. Eur J Pharmacol 881:173120 (2020). PubMed: 32325147
- Hsieh HY & Gu SH Expression of calcineurin in relation to the embryonic diapause process in the silkworm, Bombyx mori. Comp Biochem Physiol A Mol Integr Physiol 228:35-42 (2019). PubMed: 30367963
- Li Z et al. SIRT6 Suppresses NFATc4 Expression and Activation in Cardiomyocyte Hypertrophy. Front Pharmacol 9:1519 (2018). PubMed: 30670969
- Xu SC et al. Bezafibrate Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis. PPAR Res 2017:5789714 (2017). PubMed: 28127304
- Xiao L et al. Sanggenon C protects against pressure overload-induced cardiac hypertrophy via the calcineurin/NFAT2 pathway. Mol Med Rep 16:5338-5346 (2017). PubMed: 28849031