製品の概要

  • 製品名Anti-CAIN antibody
    CAIN 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to CAIN
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 1000 - 1100 of Human CAIN.

    (Peptide available as ab88931.)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Mouse Skeletal Muscle Tissue Lysate, and in the following whole cell lysates: SHSY-5Y; SK N SH; TE 671.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab76600 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 246 kDa (predicted molecular weight: 246 kDa).

ターゲット情報

  • 機能May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals.
  • 組織特異性Widely expressed in different tissues.
  • 配列類似性Contains 6 TPR repeats.
  • 翻訳後修飾Activated through PKC-mediated hyperphosphorylation.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • A330070M20Rik antibody
    • Cabin 1 antibody
    • CABIN_HUMAN antibody
    • Cabin1 antibody
    • CAIN antibody
    • Calcineurin binding protein cabin 1 antibody
    • Calcineurin inhibitor antibody
    • Calcineurin-binding protein cabin-1 antibody
    • KIAA0330 antibody
    • PPP3IN antibody
    see all

Anti-CAIN antibody 画像

  • All lanes : Anti-CAIN antibody (ab76600) at 1 µg/ml

    Lane 1 : SHSY-5Y (Human neuroblastoma cell line) Whole Cell Lysate
    Lane 2 : SK N SH (Human neuroblastoma) Whole Cell Lysate
    Lane 3 : Skeletal Muscle (Mouse) Tissue Lysate
    Lane 4 : TE 671 (Human Rhabdomyosarcoma) Whole Cell Lysate

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 246 kDa
    Observed band size : 246 kDa
    Additional bands at : 35 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 8 minutes

Anti-CAIN antibody (ab76600) 使用論文

This product has been referenced in:
  • Müller S  et al. Phosphorylation and DNA binding of HJURP determine its centromeric recruitment and function in CenH3(CENP-A) loading. Cell Rep 8:190-203 (2014). WB . Read more (PubMed: 25001279) »

See 1 Publication for this product

Product Wall

Thank you for contacting us. We are sorry; ab57137 is no longer included in our product range. We apologize for the inconvenience caused. Could we recommend few other products from our catalogue? We have ab3349 and ab76600 antibodies available ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"