製品の概要

  • 製品名CAD peptide

製品の詳細

  • 由来Synthetic

特性

Our Abpromise guarantee covers the use of ab8432 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking

    Western blot

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    PBS with 0.1% BSA 0.02% sodium azide pH7.2

関連情報

  • 別名
    • Aspartate carbamoyltransferase
    • Aspartate transcarbamylase
    • CAD protein
    • CAD trifunctional protein
    • Carbamoyl phosphate synthetase 2
    • CPSase ATCase DHOase
    • Dihydroorotase
    • Glutamine dependent carbamoyl phosphate synthase
    • Multifunctional protein CAD
    see all
  • 関連性Carbamoyl phosphate synthetase-aspartate carbamoyltransferase-dihydroorotase (CAD) is a multifunctional protein that initiates and regulates mammalian de novo pyrimidine biosynthesis. This trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis is the rate-limiting step in the de novo pyrimidine synthetic pathway. Although most of the CAD protein in the cell is cytosolic, phosphorylation at threonine 456 localizes the protein to the nucleus. While MAPK and EGF phosphorylate CAD at threonine 456, MAPK and c-myc have been found to induce over-expression of CAD.
  • 細胞内局在Cytoplasmic and Nuclear

CAD peptide (ab8432) 使用論文

ab8432 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab8432.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"