製品の概要

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Human
    • 配列C-SPGGYSHDSRHRL
    • 領域508 to 520

関連製品

特性

Our Abpromise guarantee covers the use of ab45660 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-CACNB4 antibody (ab26060)

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • CAB4
    • CACB4_HUMAN
    • Cacnb4
    • CACNLB4
    • Calcium channel voltage dependent beta 4 subunit
    • Calcium channel voltage dependent subunit beta 4
    • Calcium channel voltage-dependent subunit beta 4
    • Dihydropyridine sensitive L type calcium channel beta 4 subunit
    • EA5
    • EIG9
    • EJM
    • EJM4
    • EJM6
    • Voltage-dependent L-type calcium channel subunit beta-4
    see all
  • 機能The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
  • 組織特異性Expressed predominantly in the cerebellum and kidney.
  • 関連疾患Genetic variations in CACNB4 are the cause of susceptibility to idiopathic generalized epilepsy type 9 (IGE9) [MIM:607682]. IGE9 is characterized by recurring generalized seizures in the absence of detectable brain lesions and/or metabolic abnormalities. Generalized seizures arise diffusely and simultaneously from both hemispheres of the brain.
    Genetic variations in CACNB4 are the cause of susceptibility to juvenile myoclonic epilepsy type 6 (EJM6) [MIM:607682]. EJM6 is a subtype of idiopathic generalized epilepsy. Patients have afebrile seizures only, with onset in adolescence (rather than in childhood) and myoclonic jerks which usually occur after awakening and are triggered by sleep deprivation and fatigue.
  • 配列類似性Belongs to the calcium channel beta subunit family.
    Contains 1 SH3 domain.
  • Information by UniProt

CACNB4 peptide (508-520) (ab45660) 使用論文

ab45660 has not yet been referenced specifically in any publications.

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